- Basic information
- CohesinDB ID: CDBP00420926
- Locus: chr21-44184317-44187032
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Data sourse: GSE206145-GSE177045, ENCSR000DZP, GSE67783, GSE72082, GSE86191, GSE98367, ENCSR000HPG, ENCSR000BLY, GSE111913, GSE206145, GSE85526, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE68388, GSE83726, GSE103477, ENCSR703TNG, GSE25021, GSE50893
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Cell type: RH4, GM2610, HuCC-T1, RPE, GM2630, Fibroblast, HEKn, IMR-90, K-562, Monocytes, GM12878, GM2588, SK-N-SH, RT-112, THP-1, Macrophage, MCF-7, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.789
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
62% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 27%,
"7_Enh": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): TRPM2,CFAP410,PFKL,GATD3A,TSPEAR,TRAPPC10
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 19
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160218,
ENSG00000160221,
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000175894,
- Related loop:
chr21:44050000-44075000~~chr21:44175000-44200000,
chr21:44075000-44100000~~chr21:44175000-44200000,
chr21:44175000-44200000~~chr21:44275000-44300000,
chr21:44175000-44200000~~chr21:44300000-44325000,
chr21:44175000-44200000~~chr21:44325000-44350000,
chr21:44175000-44200000~~chr21:44700000-44725000,
chr21:5025000-5050000~~chr21:44175000-44200000,
chr21:5050000-5075000~~chr21:44175000-44200000,
chr21:5075000-5100000~~chr21:44175000-44200000,