- Basic information
- CohesinDB ID: CDBP00420933
- Locus: chr21-44201022-44205224
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Data sourse: GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE138405, GSE98367, GSE25021, ENCSR879KXD, GSE101921, GSE206145-NatGen2015, GSE120943, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE131606, GSE108869, GSE94872, ENCSR000ECS, GSE115602
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Cell type: MCF-7, Macrophage, Hela-Kyoto, Fibroblast, HCT-116, Monocytes, HUVEC, HCAEC, HeLa-S3, K-562, HSPC, HuCC-T1, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.856
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
62% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 29%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): GATD3A
- Function elements
- Human SNPs: Type_1_diabetes
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 29
- Related genes and loops
- Related gene:
ENSG00000160221,
- Related loop:
chr21:44050000-44075000~~chr21:44175000-44200000,
chr21:44075000-44100000~~chr21:44175000-44200000,
chr21:44175000-44200000~~chr21:44275000-44300000,
chr21:44175000-44200000~~chr21:44300000-44325000,
chr21:44175000-44200000~~chr21:44325000-44350000,
chr21:44175000-44200000~~chr21:44700000-44725000,
chr21:5025000-5050000~~chr21:44175000-44200000,
chr21:5050000-5075000~~chr21:44175000-44200000,
chr21:5050000-5075000~~chr21:44200000-44225000,
chr21:5075000-5100000~~chr21:44175000-44200000,