- Basic information
- CohesinDB ID: CDBP00420942
- Locus: chr21-44219482-44221142
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Data sourse: ENCSR000BLD, GSE93080, GSE67783, GSE86191, GSE98367, GSE206145, GSE62063, ENCSR000BMY, ENCSR153HNT, GSE120943, GSE103477, GSE131606, GSE50893
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Cell type: GM2630, H1-hESC, HCT-116, Monocytes, SNYDER, GM2610, THP-1, GM12878, Ramos, GM2588, GM12890, GM2255, K-562, B-cell, HSPC, Macrophage, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.811
- Subunit: NIPBL,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
62% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 25%,
"5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): ICOSLG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops