- Basic information
- CohesinDB ID: CDBP00420944
- Locus: chr21-44222967-44224198
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Data sourse: GSE67783, GSE98367, GSE111913, GSE206145, GSE206145-NatGen2015, GSE120943, GSE131606, GSE50893, GSE38411
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Cell type: GM2610, GM19240, RPE, GM2630, Fibroblast, GM12890, BCBL-1, GM18486, DKO, SNYDER, Monocytes, GM12878, GM12891, GM2588, GM19239, RT-112, Macrophage, GM12892, GM19238, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.778
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
62% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 36%,
"15_Quies": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): ICOSLG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 28
- Number of somatic mutations (non-coding): 14
- Related genes and loops