- Basic information
- CohesinDB ID: CDBP00420957
- Locus: chr21-44244978-44251442
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, GSE143937, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, ENCSR338DUC, GSE98367, ENCSR000BLS, GSE206145, GSE62063, ENCSR000BMY, ENCSR167MTG, GSE111913, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS
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Cell type: RH4, GM10847, GM2610, GM19240, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, GM19099, Macrophage, Ramos, GM12892, Hela-Kyoto, HCT-116, Hep-G2, GM19238, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 16% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.578
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 22%,
"13_ReprPC": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): TSPEAR,DNMT3L,ABCG1,PCBP3,AGPAT3,SLC37A1,NDUFV3,ICOSLG,ADARB1,PDXK,PKNOX1,WDR4,RRP1B,CSTB,TRAPPC10,GATD3A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 248
- Number of somatic mutations (non-coding): 98
- Related genes and loops
- Related gene:
ENSG00000160179,
ENSG00000160190,
ENSG00000160193,
ENSG00000160194,
ENSG00000160199,
ENSG00000160208,
ENSG00000160209,
ENSG00000160213,
ENSG00000160216,
ENSG00000160218,
ENSG00000160221,
ENSG00000160223,
ENSG00000142182,
ENSG00000175894,
ENSG00000197381,
ENSG00000183570,
- Related loop:
chr21:42050000-42075000~~chr21:44250000-44275000,
chr21:42225000-42250000~~chr21:44250000-44275000,
chr21:42525000-42550000~~chr21:44250000-44275000,
chr21:42875000-42900000~~chr21:44250000-44275000,
chr21:42975000-43000000~~chr21:44250000-44275000,
chr21:43200000-43225000~~chr21:44250000-44275000,
chr21:43275000-43300000~~chr21:44250000-44275000,
chr21:43300000-43325000~~chr21:44250000-44275000,
chr21:43350000-43375000~~chr21:44250000-44275000,
chr21:43675000-43700000~~chr21:44250000-44275000,
chr21:43750000-43775000~~chr21:44250000-44275000,
chr21:43825000-43850000~~chr21:44250000-44275000,
chr21:43850000-43875000~~chr21:44250000-44275000,
chr21:43875000-43900000~~chr21:44250000-44275000,
chr21:43900000-43925000~~chr21:44250000-44275000,
chr21:43950000-43975000~~chr21:44250000-44275000,
chr21:43975000-44000000~~chr21:44250000-44275000,
chr21:44000000-44025000~~chr21:44250000-44275000,
chr21:44025000-44050000~~chr21:44250000-44275000,
chr21:44050000-44075000~~chr21:44250000-44275000,
chr21:44075000-44100000~~chr21:44250000-44275000,
chr21:44150000-44175000~~chr21:44250000-44275000,
chr21:44250000-44275000~~chr21:44475000-44500000,
chr21:44250000-44275000~~chr21:44675000-44700000,
chr21:44250000-44275000~~chr21:45125000-45150000,
chr21:44250000-44275000~~chr21:45900000-45925000,
chr21:5025000-5050000~~chr21:44225000-44250000,
chr21:5025000-5050000~~chr21:44250000-44275000,
chr21:5050000-5075000~~chr21:44250000-44275000,
chr21:5100000-5125000~~chr21:44250000-44275000,