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Basic information

CohesinDB ID: CDBP00420964

Locus: chr21-44273834-44274503

Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045, GSE67783

Cell type: MCF-7, Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 74% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 59%, "14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, XBP1, FOXA1, ATF3, THAP1, CBFB, TP63, ZNF736, ELF1, TEAD1, SNAI2, ESR1, OCA2, USF2, CTCF, JUN, PAX8, E2F6, E2F4, ZNF528, GTF2F1, TFAP2C, EED, POU2F2, BRD1, MYCN, POU5F1, RUNX1T1, ZNF263, ZNF317, ZBTB48, ZSCAN5A, ERG2, ERG, ASCL1, OGG1, ETS1, MYC, SMARCA4, GRHL3, STAT3, XRCC5, IKZF1, DNMT3B, HNRNPH1, NR3C1, EZH2, SPI1, KLF17, PCBP1, GATAD2B, MXD3, ZGPAT, RUNX1, SMC1A, CRY1, SIN3A, ZFX, TET2, ERG3, CBX8, ZNF384, TAF15, ARNT, ZNF48, SMARCB1, CDK8, CHD1, MED1, TEAD3, TERF1, ZNF3, KLF9, NCOA1, SETDB1, BCL11A, HNRNPLL, AATF, SMC3, STAG1, NFATC3, TRP47, CBFA2T2, PPARG, FOXA2, ZNF316, EBF1, ZNF600, WT1, YY1, RELA, BRG1, MCM3, SP140, ZIC2, HIF1A, MAX, NRIP1, ZNF143, CBX2, PLAG1, KDM5B, NFKB1, EGR2, KAT8, AR, RXR, HEXIM1, HSF1, ZBTB26, RNF2, BRD4, CLOCK, MAZ, AHR

Target gene symbol (double-evidenced CRMs): GATD3A,ADARB1,TSPEAR,ABCG1,WDR4,AGPAT3,PDXK,RRP1B,NDUFV3,CSTB,PCBP3,PKNOX1,SLC37A1,TRAPPC10

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000160179, ENSG00000160190, ENSG00000160193, ENSG00000160194, ENSG00000160199, ENSG00000160208, ENSG00000160209, ENSG00000160213, ENSG00000160216, ENSG00000160218, ENSG00000160221, ENSG00000175894, ENSG00000197381, ENSG00000183570,

eachgene

Deatailed information for cohesin site CDBP00420964