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Basic information

CohesinDB ID: CDBP00420966

Locus: chr21-44277399-44277711

Data sourse: GSE206145-NatGen2015, ENCSR153HNT

Cell type: K-562, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 74% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 62%, "14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, XBP1, PATZ1, FOXA1, SUZ12, ZFHX2, HDGF, ATF3, RUNX3, PRDM1, PAX5, KLF5, BCLAF1, RBM39, ESR1, USF2, CTCF, TCF12, EP300, KLF1, DPF2, ZNF528, TFAP2C, EED, GLIS1, POU2F2, CHD8, MYCN, POU5F1, TOP2A, MTA2, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ERG2, SP4, HNF4G, ASCL1, ZBTB8A, MYC, EZH1, SMARCA4, GRHL3, GABPA, PRDM14, IKZF1, DNMT3B, NR3C1, SRSF3, HNRNPL, KMT2A, SPI1, KLF17, GATAD2B, MXD3, SMARCA5, RELB, HCFC1R1, RUNX1, SIRT6, ZFX, TET2, CBX8, ERG3, ZNF770, SMARCC1, ZNF384, OSR2, BACH1, PRDM9, FOS, CDK8, MED1, TEAD3, ZEB1, SCRT2, ZNF3, NCOA1, BCL11A, HNRNPLL, TCF3, AATF, SMC3, STAG1, MLLT1, NFATC3, TRP47, CBFA2T2, FOXA2, EBF1, ZNF600, GTF2B, WT1, ZNF30, HOXB13, YY1, RELA, BRG1, SP140, ZFP36, ZIC2, HIF1A, GATA3, KLF15, MAX, SPIB, ZNF143, CBX2, PLAG1, ZNF592, SP7, NEUROG2, NR2F1, KDM5B, ZNF687, ZBTB6, NFKB1, MYOD1, EGR2, PHOX2B, BHLHE40, AR, EGLN2, HEXIM1, ZBTB26, RNF2, HSF1, BRD4, SCRT1, CLOCK, MAZ, ZSCAN23, AHR

Target gene symbol (double-evidenced CRMs): PWP2,RRP1,TRAPPC10,GATD3A,CSTB,AGPAT3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000160213, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000241945, ENSG00000160221,

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Deatailed information for cohesin site CDBP00420966