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Basic information

CohesinDB ID: CDBP00420973

Locus: chr21-44344069-44346159

Data sourse: GSE67783, GSE86191, GSE98367, GSE116868, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT

Cell type: RPE, Fibroblast, HCT-116, Monocytes, MB157, K-562, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 74% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 44%, "15_Quies": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF384, CEBPG, NANOG, CEBPB, CEBPA, SMAD2, ZNF558, OTX2, KDM1A

Target gene symbol (double-evidenced CRMs): ITGB2-AS1,SUMO3,HSF2BP,LRRC3,TSPEAR,CSTB,PCBP3,ITGB2,RRP1B,CFAP410,SLC19A1,UBE2G2,TRAPPC10,PDXK,GATD3A,SLC37A1,FAM207A,ADARB1,TRPM2,PKNOX1,COL18A1,PTTG1IP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene: ENSG00000160190, ENSG00000160199, ENSG00000160207, ENSG00000160208, ENSG00000160209, ENSG00000160213, ENSG00000160218, ENSG00000160221, ENSG00000160226, ENSG00000142185, ENSG00000160233, ENSG00000175894, ENSG00000184787, ENSG00000184900, ENSG00000183255, ENSG00000160255, ENSG00000227039, ENSG00000160256, ENSG00000197381, ENSG00000182871, ENSG00000173638, ENSG00000183570,

eachgene

Deatailed information for cohesin site CDBP00420973