Deatailed information for cohesin site CDBP00420977

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  • Basic information
  • CohesinDB ID: CDBP00420977
  • Locus: chr21-44362803-44363087
  • Data sourse: GSE86191, GSE98367
  • Cell type: HCT-116, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: Rad21,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 74% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 33%, "14_ReprPCWk": 31%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, RXRB, MLL4, KDM3A, ZBTB7B, HDGF, THAP1, ZBTB44, PAX5, TEAD1, LMO2, OCA2, MED26, SOX5, E2F4, ZNF674, ZNF410, ZNF528, GATAD2A, POU5F1, ZNF263, TOP2A, BRD3, CTBP1, STAT1, ZNF134, SAP130, ERG, ZBTB21, SMARCA4, RFX1, RCOR1, NR2F6, CEBPB, CREB1, GABPB1, ZHX2, MIXL1, ZNF257, KLF17, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, HCFC1R1, RUNX1, CEBPA, NKX2-2, HDAC1, CRY1, TET2, SP5, SMARCC1, PRDM10, ZBTB2, TFDP1, ZBTB10, FOXM1, SP2, SMARCB1, TERF1, SMAD1, NR1H2, C11orf30, MBD1, IKZF5, ARID2, ZNF337, ELL2, NFATC3, CBFA2T2, CBX3, CREM, CHD2, ZSCAN16, WT1, JUNB, MCM3, MAF1, PLAG1, KLF4, ZFP69B, ZBTB6, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, ZBTB26, ILF3, ZNF316, FOSL1, ZNF660, XBP1, PBX2, HNRNPK, ATF3, THRB, ZFP64, DPF1, TP63, MITF, JMJD1C, ELF1, RBM39, KLF10, CTCF, JUN, MNT, ZBTB20, RYBP, DPF2, ZNF423, ZNF280A, PDX1, TFAP2C, RBPJ, MLX, ZSCAN21, ZBTB17, ZBTB48, ZNF317, SRF, KDM4A, HOMEZ, MIER3, VDR, NR3C1, ESRRA, KMT2A, KLF8, GRHL2, ZSCAN29, NFIL3, THAP11, EZH2phosphoT487, SOX13, AFF4, SP3, ARNT, NFIB, BACH1, ZNF48, PRDM9, ZEB2, ZNF10, HMGXB4, TEAD3, ZXDB, KLF9, USF1, BCL11A, SP1, TFAP2A, ATF7, ASH2L, GLIS2, SMC3, STAG1, ZNF394, TRP47, AGO1, MTA3, MAFF, ESR2, ZNF580, ZKSCAN1, KDM1A, BRG1, ZIC2, PCGF1, GATA3, KLF15, NRIP1, ZNF143, MTA1, ZNF141, TP53, ZNF334, ZSCAN22, NFKB1, PHF5A, BRD2, KAT8, EGR1, RB1, RNF2, BRD4, JUND, CUX1, ZSCAN23, PGR, SOX2, PATZ1, LEO1, TFAP4, CHD7, ZNF444, MXD4, ZNF189, SMARCE1, KLF6, ESR1, SND1, KLF1, E2F6, TRIM24, PRKDC, GTF2F1, GLIS1, POU2F2, ZSCAN5A, ERG2, SP4, TBP, HNF4G, OGG1, ETS1, MYC, KLF12, GABPA, STAT3, IKZF1, DNMT3B, SRSF3, EZH2, ZNF652, SPI1, PCBP1, HDAC2, GATAD2B, NCOA2, ZNF76, ZNF554, ETV5, BCL6, SIN3A, ERG3, RARA, NFYC, ZNF35, ZNF133, TAF15, CREBBP, ZNF384, SMAD4, CBFA2T3, ZEB1, ZNF264, MAFK, HNF4A, REST, HNRNPLL, BCOR, FOXP1, AATF, PPARG, ZNF692, ZNF30, ZNF574, RELA, TARDBP, MAX, ZNF592, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, MYOD1, AR, ZNF324, HEXIM1, DMAP1, AHR, MBD3, FOSL2, HMG20A, MEIS2, SUZ12, ZFHX2, ZNF90, INSM2, NFIC, KLF14, ZNF629, TRIM28, RCOR2, USF2, EP300, RAD51, ZNF512B, E2F1, TEAD4, FOXA3, ZNF175, EED, BRD1, MYCN, ID3, GATAD1, ARID3A, ASCL1, ZNF341, RAD21, GRHL3, PROX1, XRCC5, ZNF614, ZNF639, TFE3, HBP1, ZGPAT, ATF1, PTBP1, MAFG, SMC1A, CBX1, SIRT6, ZNF335, ZFX, SMAD3, CDK6, OSR2, ZNF184, GR, PBX4, NRF1, CHD1, FOS, TGIF2, MED1, KDM6B, SCRT2, ZNF3, L3MBTL2, SETDB1, KLF16, ZBTB7A, PHIP, TCF3, SKI, FOXA2, RBBP5, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, SP140, HIF1A, GATA1, CEBPG, SP7, NCOA3, NR2F2, ZNF687, BHLHE40, NFKBIZ, MAZ, ZNF440
  • Target gene symbol (double-evidenced CRMs): ADARB1,LRRC3,TRPM2,UBE2G2,TSPEAR
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 4
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000142185, ENSG00000160233, ENSG00000175894, ENSG00000184787, ENSG00000197381,
  • Related loop: chr21:43200000-43225000~~chr21:44350000-44375000, chr21:44350000-44375000~~chr21:44450000-44475000, chr21:44350000-44375000~~chr21:44475000-44500000, chr21:44350000-44375000~~chr21:44725000-44750000, chr21:44350000-44375000~~chr21:44750000-44775000, chr21:44350000-44375000~~chr21:44775000-44800000, chr21:44350000-44375000~~chr21:45125000-45150000, chr21:44350000-44375000~~chr21:45200000-45225000,
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