- Basic information
- CohesinDB ID: CDBP00420982
- Locus: chr21-44382365-44382932
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
74% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 32%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: YBX1, POU2F2, CHD8, FOXA2, HDAC1, MYCN, ZFX, CTBP1, MTA2, ZBTB17, ZBTB48, ZSCAN5A, WT1, XBP1, LEO1, HOXB13, ZNF300, RELA, ZBTB2, CREBBP, GATA4, RFX1, CHD7, SP140, NRF1, HIF1A, NKX2-1, GATA3, APC, GATA1, MTA1, ZNF143, DACH1, CBX2, GMEB1, NR3C1, ZNF573, MCM7, TFAP2C, NR2F1, ZNF3, ESR1, PKNOX1, TP53, ZNF547, GRHL2, CTCF, JUN, AR, HDAC2, GATA2, GATAD2B, ZNF366, HSF1, ZBTB26, BCOR, CLOCK, MAZ, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): TRPM2,TSPEAR,PCBP3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 128
- Number of somatic mutations (non-coding): 0
- Related genes and loops