- Basic information
- CohesinDB ID: CDBP00420985
- Locus: chr21-44393048-44393242
-
Data sourse: GSE25021, GSE68388
-
Cell type: MCF-7, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
74% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PPARG, FOXA2, POU5F1, SOX2, ZFX, ZNF534, ZNF317, ZNF454, ZBTB48, FOXA1, LEO1, HOXB13, ZNF18, MYC, GATA4, ZFP64, ARNT, PBX4, GRHL3, OTX2, GATA3, KLF15, FOS, ZNF143, KLF4, JMJD1C, NCOA3, TEAD1, CREB1, ESR1, CTCF, KLF1, KLF17, GATA6, DPF2, CUX1, STAG1
- Target gene symbol (double-evidenced CRMs): PCBP3,TSPEAR,TRPM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops