- Basic information
- CohesinDB ID: CDBP00420990
- Locus: chr21-44398443-44398768
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Data sourse: ENCSR703TNG, GSE86191
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Cell type: MCF-7, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
74% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 57%,
"5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, TRIM25, ZSCAN5C, ZNF660, SOX2, XBP1, PATZ1, FOXA1, HLF, SUZ12, RBFOX2, LEO1, PBX2, UBTF, ZNF28, ZFHX2, HNRNPK, HDGF, ATF3, BMI1, ZNF362, ZBTB5, RUNX3, PRDM1, KLF14, CBFB, ATF4, ZNF189, SMARCE1, TP63, ZSCAN4, ZNF467, MAF, ZNF629, ELF1, TRIM28, TEAD1, ZNF121, LMO2, ESR1, OCA2, MED26, HDAC8, USF2, CTCF, JUN, TCF12, KLF1, E4F1, MNT, ZNF695, GATA6, DPF2, PAX8, SOX4, TRIM24, IRF4, ZNF512B, TEAD4, ZNF92, ZNF175, FOXA3, GTF2F1, GATAD2A, TFAP2C, GLIS1, JARID2, POU2F2, CHD8, NANOG, ZSCAN5D, MYCN, ZNF263, BRD3, TOP2A, POU5F1, CTBP1, MTA2, ZBTB1, ZBTB48, ZSCAN5A, ZSCAN21, NONO, SRF, MLLT3, DDX5, BAHD1, ERG2, SP4, ERG, ZBTB21, OGG1, ZNF341, ETS1, MYC, SMARCA4, RFX1, RAD21, GRHL3, FOXK2, GABPA, STAT3, XRCC5, APC, NKX3-1, PRDM14, IKZF1, ZNF398, TERF2, DNMT3B, NR2F6, VDR, NFRKB, NR3C1, CEBPB, STAT5B, CREB1, EZH2, KLF8, GRHL2, FEZF1, GABPB1, ZHX2, ZNF436, HES1, SPI1, IRF1, ZNF257, PCBP1, HDAC2, GATA2, SSRP1, KLF17, GATAD2B, FLI1, SMARCA5, NFIL3, NCOA2, ZNF554, ETV5, RUNX1, CBX1, BCL6, HDAC1, SIRT6, SMC1A, CRY1, SIN3A, ZFX, ZNF335, CEBPA, SMAD3, PCBP2, TET2, ERG3, ZNF549, PRDM10, IRF2, CREBBP, RARA, ZNF384, TAF15, NOTCH1, RUNX2, ZNF35, GATA4, OSR2, ZNF184, SP3, ARNT, NFIB, ZNF48, PRDM9, SMAD4, ZEB2, ZNF518A, ATF2, SP2, FOS, CDK8, CHD1, MED1, TEAD3, ZEB1, MYB, SCRT2, ZNF3, NR1H2, L3MBTL2, EVI1, SREBF2, HIF2A, MAFK, BCL11A, SP1, PHF20, REST, ARID1A, ZNF479, ATF7, ZNF605, CTBP2, HNRNPLL, TCF3, AATF, SMC3, STAG1, MLLT1, TRP47, CBFA2T2, ZNF283, ZNF316, AGO1, FOXA2, ZNF207, CREM, NFATC1, ZSCAN16, ZNF692, WT1, ESR2, ZNF662, ZBTB33, CDK9, BCL3, ZKSCAN1, KDM1A, YY1, RELA, TARDBP, NEUROD1, MCM3, SP140, ZFP36, HIF1A, GATA3, KLF15, TAL1, MAX, MAF1, NRIP1, GATA1, ZNF143, PLAG1, ZFP69B, KLF4, ZNF592, NCOA3, NR2F2, CEBPG, SP7, NR2F1, KDM5B, TP53, PKNOX1, ZNF687, EGR2, PHOX2B, BRD2, BHLHE40, AR, RXR, YAP1, ZNF324, EGLN2, ZNF366, HEXIM1, EGR1, ZNF280D, HSF1, BRD4, JUND, CLOCK, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): PCBP3,TRPM2,TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops