Deatailed information for cohesin site CDBP00421002

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  • Basic information
  • CohesinDB ID: CDBP00421002
  • Locus: chr21-44431429-44432042
  • Data sourse: GSE120943, GSE67783, GSE98367
  • Cell type: Monocytes, HSPC, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,SMC1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 74% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 52%, "9_Het": 20%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, TRIM25, FOSL1, XBP1, PATZ1, FOXA1, SUZ12, RBFOX2, LEO1, UBTF, RXRB, KDM3A, HNRNPK, ZNF90, ATF3, CTCFL, PRDM1, ZNF444, CBFB, ZNF189, PAX5, TP63, KLF5, TEAD1, TRIM28, ELF1, RBM39, ESR1, OCA2, PITX3, JUN, CTCF, TCF12, EP300, KLF1, BAF155, PAX8, DMAP1, TRIM24, ZNF512B, ZNF776, E2F1, FOXA3, GATAD2A, RBPJ, GLIS1, POU2F2, CHD8, ZSCAN5D, ZNF263, MYCN, TOP2A, POU5F1, CTBP1, ZBTB48, ZSCAN5A, STAT1, NONO, GATAD1, SAP130, ERG2, ERG, OGG1, ETS1, MYC, HOMEZ, RAD21, GRHL3, KLF12, RXRA, GABPA, MCRS1, STAT3, XRCC5, ZNF614, APC, PRDM14, RCOR1, HNRNPH1, DNMT3B, NR2F6, MIER3, NR3C1, HNRNPL, CREB1, EZH2, KLF8, EBF3, GABPB1, ZHX2, TFE3, KLF17, ZNF257, PCBP1, HDAC2, ZNF182, MXD3, FLI1, ZGPAT, SALL2, ETV5, RUNX1, THAP11, SMC1A, BCL6, SIRT6, EZH2phosphoT487, CRY1, SOX13, ZFX, PCBP2, ZNF770, TET2, ERG3, SP5, RARA, TAF15, NRF1, ARNT, ZBTB10, ZNF48, SMAD4, ETV6, PBX3, CHD1, FOS, HMGXB4, ZEB1, TEAD3, KDM6B, MYB, ZNF3, L3MBTL2, SREBF2, USF1, SP1, HNF4A, IKZF5, REST, ZNF479, ZBTB7A, ASH2L, HNRNPLL, MBD2, TCF3, GLIS2, AATF, SMC3, NCOR2, STAG1, SKI, TRP47, CBFA2T2, MEF2B, PPARG, AGO1, FOXA2, ZNF207, CHD2, PAF1, ZNF600, MIER2, WT1, ZNF662, ZBTB33, CDK9, HOXB13, ZNF580, KDM1A, YY1, RELA, TARDBP, ZNF148, BRG1, SP140, ZIC2, TCF4, ZFP36, GATA3, TAL1, MAX, ZNF143, PLAG1, CEBPG, NR2F2, NR2F1, KDM5B, TP53, ZNF334, EGR2, ELF3, KAT8, ARID4B, AR, HEXIM1, EGR1, HSF1, ZBTB26, BRD4, CLOCK, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): PFKL,TRAPPC10,TRPM2,CFAP410,AGPAT3,RRP1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 10
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000141959, ENSG00000160226, ENSG00000142185,
  • Related loop: chr21:43350000-43375000~~chr21:44425000-44450000, chr21:43800000-43825000~~chr21:44425000-44450000, chr21:43900000-43925000~~chr21:44425000-44450000, chr21:44050000-44075000~~chr21:44425000-44450000, chr21:44075000-44100000~~chr21:44425000-44450000, chr21:44325000-44350000~~chr21:44425000-44450000, chr21:5100000-5125000~~chr21:44425000-44450000,
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