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Basic information

CohesinDB ID: CDBP00421013

Locus: chr21-44474024-44474470

Data sourse: ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 74% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 63%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CHD8, FOXA2, EZH2phosphoT487, MYCN, CEBPA, ZFX, XBP1, ZBTB48, WT1, DUX4, FOXA1, ZBTB33, SUZ12, YY1, RELA, ATF3, MYC, ONECUT1, NFIC, MCM3, RAD21, ARNT, ZNF444, HIF1A, RXRA, NKX2-1, ATF2, XRCC5, TP63, PAX5, ZNF143, ESRRA, NCOA3, NR2F2, TRIM28, MYB, CREB1, TEAD1, EZH2, KDM5B, CTCF, SP1, SPI1, HNF4A, AR, PAX8, REST, E2F6, GATAD2B, EGR1, ZNF777, JUND, ZNF512B, MAZ, ATF1, AHR

Target gene symbol (double-evidenced CRMs): CFAP410,RRP1,PFKL,TRAPPC10,TRPM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000160214, ENSG00000160218, ENSG00000141959, ENSG00000160226, ENSG00000142185,

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Deatailed information for cohesin site CDBP00421013