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Basic information

CohesinDB ID: CDBP00421014

Locus: chr21-44474734-44475102

Data sourse: ENCSR230ZWH, ENCSR917QNE

Cell type: Liver

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 74% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 64%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CHD8, FOXA2, EZH2phosphoT487, MYCN, CEBPA, ZFX, XBP1, ZBTB48, WT1, DUX4, FOXA1, ZBTB33, SUZ12, YY1, RELA, ATF3, MYC, ONECUT1, NFIC, MCM3, RAD21, ARNT, ZNF444, HIF1A, RXRA, NKX2-1, ATF2, XRCC5, TP63, PAX5, ZNF143, ESRRA, NCOA3, NR2F2, TRIM28, MYB, CREB1, TEAD1, EZH2, KDM5B, CTCF, SP1, SPI1, HNF4A, AR, PAX8, REST, E2F6, GATAD2B, EGR1, ZNF777, JUND, ZNF512B, MAZ, ATF1, AHR

Target gene symbol (double-evidenced CRMs): GATD3A,ADARB1,PTTG1IP,FAM207A,HSF2BP,AGPAT3,TRPM2,CFAP410,TRAPPC10,ITGB2,UBE2G2,PFKL,DNMT3L,RRP1,CSTB,PCBP3,ITGB2-AS1,TSPEAR,PDXK,PWP2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160207, ENSG00000160209, ENSG00000160213, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000241945, ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000175894, ENSG00000184787, ENSG00000183255, ENSG00000160255, ENSG00000227039, ENSG00000160256, ENSG00000197381, ENSG00000183570,

eachgene

Deatailed information for cohesin site CDBP00421014