Browse_each

Basic information

CohesinDB ID: CDBP00421015

Locus: chr21-44477225-44484621

Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE139435, GSE93080, GSE67783, GSE86191, GSE36578, GSE101921, ENCSR806UKK, GSE51234, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, GSE115248, GSE168045, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE38411, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE38395, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE155828, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990

Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, GP5d, Transformed-RPE1, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, HEKn, THP-1, Ishikawa, Kelly, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, MB157, Lymphoblast, GM12878, TC-71, GM12891, GM2588, GBM39, SK-N-SH, GM19239, CNCCs-H9ESC, GM19193, HeLa-Tet-On, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, SC, A-549, HUVEC, HCAEC, GM19238, HeLa, CNCC-WT33iPSC, BGO3, Neutrophil, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 79% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.144

Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 74% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 28%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, HMG20A, XBP1, FOXA1, RXRB, ZFHX2, ATF3, MECOM, TP63, MITF, JMJD1C, ETV1, SNAI2, ESR1, OCA2, CTCF, JUN, TCF12, FOXA3, ZNF175, GATAD2A, MLX, TFAP2C, RBPJ, POU2F2, CHD8, ZNF263, MYCN, KDM4C, ZBTB48, ZSCAN5A, GATAD1, SAP130, ERG2, HNF4G, ERG, ASCL1, MYC, SMARCA4, RAD21, RXRA, GABPA, XRCC5, IKZF1, MIER3, DNMT3B, ARNTL, NR3C1, CEBPB, CREB1, EZH2, GABPB1, ZHX2, SPI1, MXD3, FLI1, DRAP1, ZGPAT, NFIL3, ZNF554, ETV5, RUNX1, THAP11, SMC1A, CEBPA, EZH2phosphoT487, SOX13, ZFX, ERG3, RARA, ARNT, ZNF48, ZEB2, SMAD4, ETV6, FOS, TEAD3, MYB, SCRT2, ZNF3, SP1, HNF4A, IKZF5, REST, ZHX1, HNRNPLL, TCF3, FOXP1, AATF, SMC3, STAG1, PPARG, FOXA2, SS18, WT1, ZBTB33, KDM1A, YY1, RELA, TARDBP, SP140, HIF1A, TAL1, MAX, CEBPG, NCOA3, PKNOX1, ELF3, KAT8, NFKBIZ, BHLHE40, YAP1, ZBTB42, EGR1, ZBTB26, HSF1, JUND, CLOCK, CUX1, MAZ, AHR

Target gene symbol (double-evidenced CRMs): UBE2G2,PCBP3,PDXK,AGPAT3,CSTB,GATD3A,TRAPPC10,DNMT3L,CFAP410,TRPM2,RRP1,PWP2,ADARB1,ITGB2,FAM207A,PFKL,HSF2BP,ITGB2-AS1,PTTG1IP,TSPEAR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 30

Related genes and loops

Related gene: ENSG00000160207, ENSG00000160209, ENSG00000160213, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000241945, ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000175894, ENSG00000184787, ENSG00000183255, ENSG00000160255, ENSG00000227039, ENSG00000160256, ENSG00000197381, ENSG00000183570,

eachgene

Deatailed information for cohesin site CDBP00421015