- Basic information
- CohesinDB ID: CDBP00421034
- Locus: chr21-44537821-44540876
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Data sourse: ENCSR000BLD, ENCSR000BTU, ENCSR338DUC, GSE67783, GSE72082, GSE86191, GSE138405, GSE116868, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE25021
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Hela-Kyoto, Hep-G2, MB157, Ishikawa, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 38%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, FOXA2, MYCN, ZFX, ZBTB48, WT1, TET2, SUZ12, HOXB13, ERG, RELA, OGG1, ATF3, MYC, ZNF84, SP140, GRHL3, ARNT, CBFB, ATF2, ZNF48, TP63, ZNF143, CDK8, DNMT3B, TRIM28, CREB1, NR2F1, EZH2, ZNF3, ESR1, GRHL2, USF2, GABPB1, CTCF, BCL11A, AR, PTBP1, HEXIM1, HSF1, BRD4, AFF1, MAZ, AATF, ATF1, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): COL18A1,TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1085
- Number of somatic mutations (non-coding): 7
- Related genes and loops