Deatailed information for cohesin site CDBP00421035


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  • Basic information
  • CohesinDB ID: CDBP00421035
  • Locus: chr21-44547626-44548710
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE67783, GSE86191, ENCSR153HNT, GSE126755
  • Cell type: MCF-7, H1-hESC, HCT-116, K-562, Neutrophil, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.933
  • Subunit: Mau2,SA1,Rad21,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 80% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "15_Quies": 24%, "7_Enh": 23%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: SOX2, FOXA1, SUZ12, ZFHX2, ZBTB7B, CHD7, TP63, MAF, ELF1, TRIM28, ESR1, OCA2, TP73, CTCF, RYBP, E2F6, ZNF410, ZNF528, TEAD4, POU2F2, CHD8, ZSCAN5D, MYCN, POU5F1, TOP2A, ZNF317, ZBTB48, STAT1, SRF, BAHD1, ERG2, TBP, ERG, OGG1, MYC, SMARCA4, RAD21, GABPA, STAT3, DNMT3B, NR3C1, EZH2, BMPR1A, SPI1, ZIM3, RUNX1, CEBPA, EZH2phosphoT487, SIRT6, ZFX, SMAD3, ERG3, ETV6, CHD1, SETDB1, USF1, ASH2L, TCF3, BCOR, ZNF394, TRP47, CBFA2T2, FOXA2, CBX3, WT1, HOXB13, KDM1A, RELA, ZIC2, GATA3, MAX, GATA1, TLE3, NR2F1, TP53, ZNF334, ELF3, BRD2, AR, RXR, EGLN2, ZBTB42, HSF1, BRD4, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): COL18A1,TSPEAR
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 6
  • Number of somatic mutations (non-coding): 2
  • Related genes and loops

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