- Basic information
- CohesinDB ID: CDBP00421036
- Locus: chr21-44549598-44553104
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Data sourse: ENCSR000BLD, GSE72082, GSE116868, GSE105028, GSE25021, GSE131606, ENCSR000BTU, GSE67783, GSE86191, GSE206145-NatGen2015, GSE120943, GSE112028, ENCSR703TNG, ENCSR338DUC, GSE98367, GSE206145, GSE85526, GSE97394, GSE110061, GSE111913, ENCSR153HNT
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Monocytes, HEKn, Hep-G2, MB157, Ishikawa, DKO, HUES64, RT-112, K-562, HeLa-Tet-On, HSPC, Macrophage, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.800
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 29%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TP63, FLI1, GRHL3, STAT3
- Target gene symbol (double-evidenced CRMs): COL18A1,TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1490
- Number of somatic mutations (non-coding): 46
- Related genes and loops