- Basic information
- CohesinDB ID: CDBP00421043
- Locus: chr21-44578510-44580767
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Data sourse: ENCSR000BLD, ENCSR000BTQ, ENCSR000BTU, ENCSR338DUC, GSE67783, GSE72082, GSE86191, GSE116868, GSE105028, ENCSR153HNT, ENCSR703TNG, GSE25021
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Cell type: MCF-7, H1-hESC, HCT-116, Hep-G2, MB157, Ishikawa, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 30%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, FOXA2, MYCN, ZFX, DUX4, ZSCAN5A, ZBTB48, FOXA1, WT1, TET2, ZFP90, HOXB13, ERG, KDM1A, RELA, OGG1, ATF3, MYC, SP140, GRHL3, ARNT, ZIC2, STAT3, TP63, ZNF143, RCOR1, ZNF736, CREB1, PIAS1, NR2F1, EZH2, ZNF3, ZNF334, SETDB1, JUN, CTCF, ZNF479, RBM25, ZNF280D, HSF1, BRD4, MAZ, AATF, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): PCBP3,TSPEAR,ADARB1
- Function elements
- Human SNPs: Cognitive_empathy
- Number of somatic mutations (coding): 1297
- Number of somatic mutations (non-coding): 195
- Related genes and loops