- Basic information
- CohesinDB ID: CDBP00421045
- Locus: chr21-44583120-44583635
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Data sourse: GSE206145-GSE177045, GSE67783, GSE72082, GSE115602
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Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 48%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, TRIM25, ZNF660, MEIS2, XBP1, FOXA1, PBX2, ATF3, RUNX3, ATF4, MITF, TEAD1, TRIM28, BCLAF1, ETV1, NFE2L2, SAP30, ESR1, OCA2, MED26, CTCF, JUN, TCF12, BAF155, E4F1, EP300, MNT, KLF1, DPF2, E2F6, TRIM24, IRF4, SOX6, E2F1, TFAP2C, JARID2, GLIS1, POU2F2, CHD8, MYCN, ZNF263, TOP2A, ID3, POU5F1, CTBP1, KDM4C, ZBTB48, DDX5, NBN, TBP, HOXC5, ERG, ZBTB21, OGG1, ZNF341, MYC, SMARCA4, ARID1B, GRHL3, PROX1, BATF3, GABPA, STAT3, IKZF1, RCOR1, NFE2, LEF1, ARNTL, NR3C1, CEBPB, ESRRA, SRSF3, CREB1, ZBTB11, EZH2, GABPB1, PHF8, SPI1, IRF1, HDAC2, GATA2, SREBF1, MXI1, ZIM3, ATF1, RUNX1, SMC1A, CBX1, HDAC1, MAFG, BCL6, ZFX, SMAD3, TET2, SMARCC1, ZNF384, CDK6, ARNT, PBX4, NRF1, ATF2, ZEB2, CBFA2T3, PBX3, FOS, MED1, TEAD3, DIDO1, MYB, PIAS1, ZNF3, L3MBTL2, SETDB1, TFAP2A, NR4A1, ATF7, ASH2L, HNRNPLL, BCOR, FOXP1, STAG1, MLLT1, TRP47, CBFA2T2, CBX3, MTA3, CREM, MEIS1, SS18, RBBP5, WT1, TCF7, HOXB13, ZNF318, ZNF589, YY1, RELA, KDM1A, JUNB, AHR, BRG1, SP140, ZIC2, HIF1A, ZFP36, OTX2, GATA3, BATF, MGA, TAL1, MAX, NRIP1, GATA1, MTA1, ZNF143, CEBPG, SP7, ZNF83, ZNF512, NR2F1, TCF7L2, KDM5B, ZNF687, PKNOX1, TP53, TBX21, BHLHE40, AR, ZBTB40, EGLN2, ZNF366, RB1, HSF1, RNF2, BRD4, ILF3, JUND, CUX1, MAZ, MEF2D, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): TSPEAR,PCBP3,ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 3
- Related genes and loops