- Basic information
- CohesinDB ID: CDBP00421048
- Locus: chr21-44599082-44599579
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Data sourse: GSE120943, GSE86191, GSE98367
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Cell type: HCT-116, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 43%,
"15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, POU2F2, PGR, FOXA2, POU5F1, MYCN, TOP2A, SOX2, ZFX, ZNF263, ZSCAN5D, SS18, ZBTB48, WT1, STAT1, FOXA1, CBX8, HOXB13, SMARCC1, ERG, TFAP4, RELA, BRG1, CHD7, RAD21, SP140, MECOM, MAX, TP63, XRCC5, MIER3, PLAG1, TEAD3, TRIM28, EZH2, TP53, OCA2, TP73, ZNF136, SETDB1, CTCF, BCL11A, BAF155, PAX3-FOXO1, AR, TAF1, GATA2, E2F6, HSF1, RNF2, ASH2L, BRD4, ZBTB26, ZNF490, FOXP1, MAZ, ZNF440, TEAD4, ZNF24, STAG1
- Target gene symbol (double-evidenced CRMs): PCBP3,TSPEAR,ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 2
- Related genes and loops