- Basic information
- CohesinDB ID: CDBP00421052
- Locus: chr21-44611739-44617566
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Data sourse: ENCSR000BLD, ENCSR167MTG, GSE67783, GSE72082, GSE86191, GSE116868, GSE25021, GSE111913, ENCSR000BLS, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, ENCSR054FKH, GSE206145, ENCSR153HNT, GSE68388, GSE131606, GSE97394
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Hep-G2, MB157, DKO, HUES64, RT-112, K-562, HSPC, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 26%,
"15_Quies": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, TRP47, CBX3, MYCN, ZNF707, ZFX, DUX4, ZNF30, ZBTB48, WT1, SRF, YY1, RELA, CREBBP, TARDBP, ASCL1, ATF3, RUNX2, MYC, SMARCA4, SP140, GRHL3, MAX, DNMT3B, CBX2, NCOA3, TRIM28, ZNF3, ESR1, LMO2, CTCF, PTBP1, HEXIM1, HSF1, TCF3, HCFC1R1, AATF, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1190
- Number of somatic mutations (non-coding): 40
- Related genes and loops