- Basic information
- CohesinDB ID: CDBP00421053
- Locus: chr21-44618432-44619258
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, GSE25021, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, GSE143937, GSE93080, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE51234, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, ENCSR000EEG, ENCSR338DUC, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, ENCSR944ZCT, GSE110061, GSE129526, ENCSR000HPG, GSE111913, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, GSE126755, ENCSR000ECS
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Cell type: MDM, RH4, SLK, CVB-hiPSC, CVI-hiPSC, Liver, GP5d, HuCC-T1, H9-hESC, RPE, Fibroblast, Ishikawa, GM12890, HeLa-S3, IMR-90, K-562, DKO, H1-hESC, GM12878, SK-N-SH, RT-112, THP-1, HUES64, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, A-549, HUVEC, HCAEC, GM19238, Neutrophil
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 24% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.644
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 38%,
"14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, TRIM25, PGR, XBP1, FOXA1, SUZ12, RXRB, ZFHX2, ATF3, CHD7, ZNF322, CBFB, TP63, ZNF736, MAF, ELF1, TRIM28, LMO2, ESR1, CTCF, SOX5, RYBP, ZNF512B, SMC1, TEAD4, TFAP2C, CHD8, BRD1, MYCN, POU5F1, RUNX1T1, ID3, ZNF263, ZBTB48, DUX4, SAP130, ERG2, ERG, ASCL1, OGG1, MYC, SMARCA4, HOMEZ, RAD21, GRHL3, GABPA, STAT3, XRCC5, PRDM14, DNMT3B, NR3C1, CEBPB, SRSF3, CREB1, EZH2, GRHL2, EBF3, SPI1, MIXL1, GATA2, GATAD2B, MXD3, FLI1, ZGPAT, HCFC1R1, ATF1, RUNX1, THAP11, BCL6, CBX1, SMC1A, EZH2phosphoT487, CEBPA, ZFX, SMAD3, TET2, ERG3, SMARCC1, CREBBP, ZBTB2, RARA, TAF15, NFIB, ARNT, NRF1, ATF2, ZNF48, SMAD4, NCAPH2, CHD1, SMARCB1, FOS, ZEB1, TEAD3, KDM6B, MYB, ZNF680, SCRT2, SMAD1, ZNF3, SETDB1, REST, ZFP69, TCF3, AATF, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, ZNF207, AGO1, ZNF44, WT1, YY1, RELA, BRG1, MCM3, SP140, ZIC2, HIF1A, OTX2, MAX, NRIP1, ZNF143, ZNF141, NR2F1, TP53, EGR2, ELF3, KAT8, TBX21, BHLHE40, AR, ARID4B, NFKBIZ, RXR, EGLN2, HEXIM1, TFIIIC, HSF1, BRD4, SCRT1, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): UBE2G2,TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops