- Basic information
- CohesinDB ID: CDBP00421055
- Locus: chr21-44626266-44630097
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Data sourse: ENCSR000BLD, ENCSR000BTU, GSE118494, GSE67783, GSE86191, GSE25021, GSE111913, GSE206145-NatGen2015, ENCSR153HNT, GSE106870, GSE38411
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Cell type: MCF-7, H1-hESC, Fibroblast, HCT-116, CVB-hiPSC, Ishikawa, RT-112, IMR-90, K-562, BCBL-1, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 24%,
"9_Het": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, TRP47, POU2F2, TRIM25, TBL1X, MYCN, SIN3A, ZFX, XBP1, ZBTB48, WT1, TET2, ERG3, ERG2, ZFHX2, YY1, RELA, ATF3, MYC, AHR, SP140, ZIC2, GRHL3, HIF1A, TP63, ZNF143, PRDM14, DNMT3B, ARNTL, NCOA3, TEAD1, MYB, EZH2, ESR1, EGR2, CTCF, TBX21, AR, ZNF257, BRD4, MAZ, AATF, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): PCBP3,TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1537
- Number of somatic mutations (non-coding): 57
- Related genes and loops