- Basic information
- CohesinDB ID: CDBP00421056
- Locus: chr21-44636179-44640011
-
Data sourse: ENCSR000BLD, ENCSR000BTU, GSE67783, GSE72082, GSE86191, GSE116868, GSE25021, GSE111913, GSE105028, GSE206145-NatGen2015, ENCSR054FKH, GSE206145, ENCSR153HNT, GSE68388, GSE131606
-
Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Hep-G2, MB157, Ishikawa, DKO, RT-112, K-562, HSPC, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 35%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CEBPA, MYCN, MEIS2, ZFX, XBP1, WT1, STAT1, FOXA1, PBX2, HOXB13, ZNF19, RELA, EZH1, ATF2, DNMT3B, CEBPB, TEAD3, ESR1, PKNOX1, CTCF, ZNF146, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): PCBP3,TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2029
- Number of somatic mutations (non-coding): 46
- Related genes and loops