Deatailed information for cohesin site CDBP00421064

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  • Basic information
  • CohesinDB ID: CDBP00421064
  • Locus: chr21-44657623-44658306
  • Data sourse: GSE67783, GSE126755, ENCSR230ZWH, GSE86191
  • Cell type: Liver, HCT-116, HSPC, Neutrophil
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.956
  • Subunit: SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 80% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "14_ReprPCWk": 27%, "15_Quies": 22%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOSL1, HMG20A, XBP1, FOXA1, ATF3, RUNX3, PRDM1, CBFB, PAX5, JMJD1C, MAF, ETV1, ESR1, OCA2, CTCF, TCF12, KLF1, LMO1, TRIM24, ZNF280A, FOXA3, KMT2B, GATAD2A, EED, POU2F2, POU5F1, MYCN, TOP2A, RUNX1T1, KDM4C, ZNF317, ZBTB48, ERG, USP7, OGG1, MYC, SMARCA4, RAD21, GRHL3, RXRA, GABPA, STAT3, PRDM14, GFI1, DNMT3B, ARNTL, VDR, CEBPB, STAT5B, KMT2A, CREB1, EZH2, BMPR1A, GABPB1, SPI1, KLF17, GATA2, ETV5, RUNX1, BCL6, SMC1A, CEBPA, EZH2phosphoT487, ZFX, CREBBP, ARNT, ZNF48, FOS, CDK8, MED1, TEAD3, KDM6B, MYB, ZNF136, SETDB1, STAT5A, SP1, REST, TCF3, FOXP1, AATF, SMC3, STAG1, TRP47, MEF2B, PPARG, CBX3, FOXA2, TBL1X, RBBP5, WT1, FOXF1, MEF2C, ZBTB33, CDK9, HOXB13, YY1, RELA, SP140, HIF1A, BATF, TAL1, MAX, ZNF143, KLF4, NCOA3, TP53, TBX21, AR, RXR, ZBTB26, HSF1, BRD4, CLOCK, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): TSPEAR,PTTG1IP,ITGB2,ADARB1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 472
  • Number of somatic mutations (non-coding): 119
  • Related genes and loops
  • Related gene: ENSG00000175894, ENSG00000183255, ENSG00000160255, ENSG00000197381,
  • Related loop: chr21:22525000-22550000~~chr21:44650000-44675000, chr21:27500000-27525000~~chr21:44650000-44675000, chr21:44475000-44500000~~chr21:44650000-44675000, chr21:44650000-44675000~~chr21:44875000-44900000, chr21:44650000-44675000~~chr21:45200000-45225000, chr21:44650000-44675000~~chr21:45325000-45350000,
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