- Basic information
- CohesinDB ID: CDBP00421070
- Locus: chr21-44670503-44671575
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, ENCSR153HNT, GSE83726
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Cell type: MCF-7, RH4, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 55%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBFA2T2, POU2F2, SMC1A, MYCN, POU5F1, RUNX1T1, ZFX, XBP1, WT1, ZSCAN5A, ZBTB48, FOXA1, TET2, KDM1A, YY1, RELA, CREBBP, SP140, ARNT, SMC3, TAL1, APC, NRIP1, ZNF143, FOS, KLF5, NCOA3, TRIM28, EZH2, ESR1, SETDB1, CTCF, USF1, GSPT2, AR, HDAC2, ZBTB42, HSF1, BRD4, E2F1, MAZ, TEAD4, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): TSPEAR,ADARB1,ITGB2,PTTG1IP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000175894,
ENSG00000183255,
ENSG00000160255,
ENSG00000197381,
- Related loop:
chr21:22525000-22550000~~chr21:44650000-44675000,
chr21:27500000-27525000~~chr21:44650000-44675000,
chr21:43575000-43600000~~chr21:44675000-44700000,
chr21:44250000-44275000~~chr21:44675000-44700000,
chr21:44475000-44500000~~chr21:44650000-44675000,
chr21:44575000-44600000~~chr21:44675000-44700000,
chr21:44650000-44675000~~chr21:44875000-44900000,
chr21:44650000-44675000~~chr21:45200000-45225000,
chr21:44650000-44675000~~chr21:45325000-45350000,