- Basic information
- CohesinDB ID: CDBP00421071
- Locus: chr21-44672289-44672609
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Data sourse: GSE105028, GSE206145-NatGen2015, GSE86191
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Cell type: Fibroblast, HCT-116, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"9_Het": 52%,
"15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, CBX3, TOP2A, ZBTB48, FOXA1, ZBTB33, OGG1, ZEB2, ZNF143, GATA1, CEBPG, CEBPB, TRIM28, PIAS1, SETDB1, CTCF, ZNF324, TRIM24, ZNF410, BRD4, ZNF280A, ZNF24, MLLT1
- Target gene symbol (double-evidenced CRMs): PTTG1IP,TSPEAR,ADARB1,ITGB2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000175894,
ENSG00000183255,
ENSG00000160255,
ENSG00000197381,
- Related loop:
chr21:22525000-22550000~~chr21:44650000-44675000,
chr21:27500000-27525000~~chr21:44650000-44675000,
chr21:43575000-43600000~~chr21:44675000-44700000,
chr21:44250000-44275000~~chr21:44675000-44700000,
chr21:44475000-44500000~~chr21:44650000-44675000,
chr21:44575000-44600000~~chr21:44675000-44700000,
chr21:44650000-44675000~~chr21:44875000-44900000,
chr21:44650000-44675000~~chr21:45200000-45225000,
chr21:44650000-44675000~~chr21:45325000-45350000,