- Basic information
- CohesinDB ID: CDBP00421072
- Locus: chr21-44674682-44674829
-
Data sourse: GSE120943, GSE98367
-
Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 51%,
"14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZSCAN4, DPF2, ZFX, TP63
- Target gene symbol (double-evidenced CRMs): TSPEAR,ADARB1,PTTG1IP,ITGB2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000175894,
ENSG00000183255,
ENSG00000160255,
ENSG00000197381,
- Related loop:
chr21:22525000-22550000~~chr21:44650000-44675000,
chr21:27500000-27525000~~chr21:44650000-44675000,
chr21:43575000-43600000~~chr21:44675000-44700000,
chr21:44250000-44275000~~chr21:44675000-44700000,
chr21:44475000-44500000~~chr21:44650000-44675000,
chr21:44575000-44600000~~chr21:44675000-44700000,
chr21:44650000-44675000~~chr21:44875000-44900000,
chr21:44650000-44675000~~chr21:45200000-45225000,
chr21:44650000-44675000~~chr21:45325000-45350000,