- Basic information
- CohesinDB ID: CDBP00421073
- Locus: chr21-44681190-44682189
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Data sourse: GSE206145, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 48%,
"15_Quies": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, RUNX1, MYC, EZH2phosphoT487, MYCN, SP140, ZBTB48, TET2, HOXB13, MITF
- Target gene symbol (double-evidenced CRMs): TSPEAR,HSF2BP,DNMT3L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 423
- Number of somatic mutations (non-coding): 107
- Related genes and loops