- Basic information
- CohesinDB ID: CDBP00421074
- Locus: chr21-44682701-44683068
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Data sourse: ENCSR000BLD, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, H1-hESC, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 48%,
"15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, NME2, XBP1, FOXA1, SUZ12, TFAP4, ATF3, NFIC, CBFB, TRIM28, ZNF121, NFE2L2, ESR1, CTCF, TCF12, DPF2, TRIM24, TEAD4, POU2F2, CHD8, MYCN, TOP2A, CTBP1, ZBTB17, ZBTB48, ERG, ASCL1, MYC, ARID1B, GRHL3, STAT3, IKZF1, RCOR1, DNMT3B, ZNF639, NFE2, ZNF285, CEBPB, CREB1, EZH2, HDAC2, INTS13, RUNX1, MAFG, SMC1A, HDAC1, NKX2-2, EZH2phosphoT487, SIN3A, ZFX, TET2, ARNT, BACH1, ZEB2, CBFA2T3, FOS, CEBPD, SCRT2, C11orf30, STAT5A, MAFK, AATF, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, MTA3, MAFF, WT1, MEF2C, YY1, RELA, NEUROD1, SP140, ZFP36, HIF1A, MAF1, MAX, TAL1, GATA1, TP53, AR, RXR, HEXIM1, NCOR1, BRD4, SCRT1, ILF3, JUND, MAZ, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): DNMT3L,TSPEAR,HSF2BP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops