- Basic information
- CohesinDB ID: CDBP00421085
- Locus: chr21-44721222-44721639
-
Data sourse: GSE120943, GSE67783, GSE98367
-
Cell type: Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"14_ReprPCWk": 74%,
"13_ReprPC": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: TBX5, GRHL3
- Target gene symbol (double-evidenced CRMs): FAM207A,TSPEAR,TRPM2,ITGB2,ITGB2-AS1,GATD3A,PFKL,CFAP410
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000160221,
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000175894,
ENSG00000160255,
ENSG00000227039,
ENSG00000160256,
- Related loop:
chr21:43350000-43375000~~chr21:44725000-44750000,
chr21:44075000-44100000~~chr21:44725000-44750000,
chr21:44175000-44200000~~chr21:44700000-44725000,
chr21:44325000-44350000~~chr21:44700000-44725000,
chr21:44325000-44350000~~chr21:44725000-44750000,
chr21:44350000-44375000~~chr21:44725000-44750000,
chr21:44375000-44400000~~chr21:44725000-44750000,
chr21:44475000-44500000~~chr21:44725000-44750000,
chr21:44500000-44525000~~chr21:44700000-44725000,
chr21:44500000-44525000~~chr21:44725000-44750000,
chr21:44509197-44511724~~chr21:44717965-44719686,
chr21:44509213-44512100~~chr21:44718108-44719341,
chr21:44509225-44511899~~chr21:44717741-44719707,
chr21:44509481-44512016~~chr21:44717736-44719579,
chr21:44509926-44511467~~chr21:44718171-44719367,
chr21:44525000-44550000~~chr21:44725000-44750000,
chr21:44575000-44600000~~chr21:44725000-44750000,
chr21:44625000-44650000~~chr21:44725000-44750000,
chr21:44700000-44725000~~chr21:44925000-44950000,