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Basic information

CohesinDB ID: CDBP00421094

Locus: chr21-44737533-44737682

Data sourse: ENCSR054FKH, GSE72082, ENCSR000BKV, ENCSR167MTG

Cell type: K-562, Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 80% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "9_Het": 69%, "15_Quies": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MBD3, NFIA, FOSL1, PGR, HMG20A, SOX2, XBP1, FOXA1, SUZ12, RXRB, PBX2, ZNF28, ZFHX2, KDM3A, TFAP4, ZNF529, TSC22D4, ATF3, NFIC, THRB, ZFP64, THAP1, ZNF112, CHD7, ZNF444, CBFB, MXD4, SMARCE1, TP63, MITF, ZNF320, ZNF736, HDAC3, JMJD1C, ZNF586, TEAD1, TRIM28, ELF1, ETV1, ZNF26, LMO2, ESR1, MLL, ZNF217, RCOR2, USF2, CTCF, JUN, TCF12, EP300, BAF155, KLF1, SOX5, GATA6, DPF2, SOX4, E2F6, RFX5, ZNF518A, NR5A2, ZNF528, ZNF350, ZNF280A, FOXA3, ZNF175, ZNF92, GTF2F1, GATAD2A, TFAP2C, RBPJ, MLX, GLIS1, POU2F2, NANOG, BRD1, MYCN, POU5F1, ZNF263, ZNF778, TOP2A, CTBP1, ID3, ZBTB17, ZBTB48, DUX4, ZSCAN5A, RUNX1T1, SRF, GATAD1, SAP130, NBN, ERG2, HNF4G, ERG, HOXC5, PBX1, ASCL1, OGG1, ETS1, MYC, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, PROX1, GABPA, STAT3, XRCC5, ZNF614, NKX3-1, PRDM14, IKZF1, RCOR1, DNMT3B, NR2F6, NFE2, VDR, MIER3, NR3C1, ESRRA, CEBPB, ZNF667, HNRNPL, CREB1, CCAR2, EZH2, KLF8, GRHL2, ZNF652, GABPB1, SPI1, TFE3, MIXL1, ZNF257, PCBP1, HDAC2, GATA2, ZNF644, GATAD2B, MXD3, FLI1, DRAP1, ZGPAT, ZNF789, MXI1, HHEX, ZNF490, HCFC1R1, NFIL3, NCOA2, ZIM3, ZNF554, MYF5, ETV5, PTBP1, RUNX1, THAP11, BCL6, ZBTB24, HDAC1, CEBPA, SIRT6, CBX1, SIN3A, ZFX, ZNF534, SOX13, AFF4, SMAD3, TET2, ERG3, SP5, TWIST1, PRDM10, SMARCC1, ZNF549, RARA, ZNF384, CREBBP, ZXDC, TAF15, ZNF169, NOTCH1, GATA4, GR, ZNF184, ARNT, NRF1, DAXX, NFIB, ATF2, ZNF48, ZEB2, HMBOX1, SMAD4, CBFA2T3, NCAPH2, PBX3, FOS, CDK8, CHD1, SMARCB1, HMGXB4, MED1, TEAD3, KDM6B, MYB, SCRT2, PIAS1, ZNF680, SETDB1, SREBF2, TBX5, ZNF22, USF1, BCL11A, TFAP2A, NIPBL, HNF4A, SP1, IKZF5, ZBTB7A, ASH2L, HNRNPLL, CTBP2, AFF1, TCF3, MBD2, FOXP1, AATF, SMC3, ELL2, STAG1, NFATC3, SKI, TRP47, CBFA2T2, KLF13, PPARG, FOXA2, AGO1, CREM, CHD2, SS18, MIER2, ZSCAN16, GTF2B, WT1, MAFF, ZNF662, MEF2C, HOXB13, ZNF580, FOXO3, KDM1A, YY1, RELA, KLF7, TARDBP, MPHOSPH8, NEUROD1, BRG1, ZNF510, ZNF610, SP140, ZFP36, HIF1A, OTX2, GATA3, ZNF311, TAL1, MAX, NRIP1, GATA1, ZNF143, MTA1, PLAG1, TLE3, CEBPG, NCOA3, NR2F2, ZNF544, NR2F1, NEUROG2, KDM5B, TP53, PKNOX1, ZNF687, ZNF547, ZNF334, MYOD1, EGR2, ELF3, PHF5A, KAT8, ZFP28, BHLHE40, AR, ARID4B, NFKBIZ, ZNF324, EGR1, HEXIM1, TFIIIC, HSF1, ZBTB26, NCOR1, BRD4, JUND, SCRT1, ZNF280D, CUX1, MAZ, ZNF248, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): TRAPPC10,PFKL,TSPEAR,TRPM2,CFAP410

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000160218, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000175894,

eachgene

Deatailed information for cohesin site CDBP00421094