- Basic information
- CohesinDB ID: CDBP00421098
- Locus: chr21-44747978-44748295
-
Data sourse: ENCSR703TNG, GSE67783, GSE72082
-
Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 40%,
"15_Quies": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, RELA, CREBBP, NR3C1, PGR, NCOA3, ELF1, NR2F2, ARNT, ESR1, HIF1A, ESR2, FOXA1, GATA3, GRHL2, NCOA2, NRIP1
- Target gene symbol (double-evidenced CRMs): PFKL,TSPEAR,CFAP410,TRPM2,TRAPPC10
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000160218,
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000175894,
- Related loop:
chr21:43350000-43375000~~chr21:44725000-44750000,
chr21:43950000-43975000~~chr21:44750000-44775000,
chr21:44075000-44100000~~chr21:44725000-44750000,
chr21:44325000-44350000~~chr21:44725000-44750000,
chr21:44325000-44350000~~chr21:44750000-44775000,
chr21:44350000-44375000~~chr21:44725000-44750000,
chr21:44350000-44375000~~chr21:44750000-44775000,
chr21:44375000-44400000~~chr21:44725000-44750000,
chr21:44475000-44500000~~chr21:44725000-44750000,
chr21:44500000-44525000~~chr21:44725000-44750000,
chr21:44500000-44525000~~chr21:44750000-44775000,
chr21:44509093-44511625~~chr21:44741922-44743349,
chr21:44509121-44511913~~chr21:44741499-44743338,
chr21:44509161-44511662~~chr21:44741531-44743454,
chr21:44509189-44512062~~chr21:44741776-44743366,
chr21:44509197-44511724~~chr21:44742007-44743217,
chr21:44509198-44511827~~chr21:44741970-44743275,
chr21:44509207-44511848~~chr21:44741832-44743353,
chr21:44509213-44512100~~chr21:44741837-44743290,
chr21:44509225-44511899~~chr21:44741727-44743366,
chr21:44509231-44511792~~chr21:44741857-44743273,
chr21:44509236-44511997~~chr21:44741562-44743367,
chr21:44509239-44511525~~chr21:44741601-44743335,
chr21:44509243-44511788~~chr21:44741569-44743400,
chr21:44509249-44511508~~chr21:44741746-44743390,
chr21:44509259-44511819~~chr21:44741806-44743375,
chr21:44509266-44512046~~chr21:44741597-44743406,
chr21:44509284-44511597~~chr21:44741782-44743295,
chr21:44509488-44511948~~chr21:44741900-44743346,
chr21:44509542-44511909~~chr21:44748109-44749367,
chr21:44509689-44512016~~chr21:44741924-44743372,
chr21:44509692-44511946~~chr21:44741525-44743441,
chr21:44509755-44512096~~chr21:44741909-44743377,
chr21:44509876-44511623~~chr21:44741970-44743300,
chr21:44509886-44511719~~chr21:44741926-44743364,
chr21:44525000-44550000~~chr21:44725000-44750000,
chr21:44575000-44600000~~chr21:44725000-44750000,
chr21:44617977-44619406~~chr21:44741926-44743364,
chr21:44618046-44619706~~chr21:44741900-44743346,
chr21:44625000-44650000~~chr21:44725000-44750000,
chr21:44750000-44775000~~chr21:45725000-45750000,
chr21:5025000-5050000~~chr21:44750000-44775000,
chr21:5100000-5125000~~chr21:44750000-44775000,