Browse_each

Basic information

CohesinDB ID: CDBP00421106

Locus: chr21-44780867-44781685

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 49%, "4_Tx": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, XBP1, FOXA1, RBFOX2, RXRB, PBX2, LEO1, KDM3A, HDGF, ATF3, ZBTB44, CHD7, ATF4, CBFB, MXD4, PAX5, MITF, ZNF736, SFPQ, CDX2, KLF5, TEAD1, ELF1, ETV1, SNAI2, KLF6, NFE2L2, RCOR2, ESR1, OCA2, MLL, RBM39, HDAC8, CTCF, JUN, BAF155, KLF1, EP300, MNT, SOX5, PAX8, TRIM24, FOXA3, ZNF175, GATAD2A, PDX1, RBPJ, MLX, TFAP2C, EED, POU2F2, CHD8, MYCN, ZNF263, TOP2A, POU5F1, ZNF317, ZBTB17, ZBTB48, GATAD1, DDX5, SAP130, ARID3A, TBP, ERG, OGG1, ETS1, MYC, ONECUT1, SMARCA4, ARID1B, FOXP2, RAD21, HOMEZ, GRHL3, RXRA, PROX1, NKX2-1, STAT3, ZNF614, XRCC5, NKX3-1, MIER3, DNMT3B, NR2F6, NFRKB, ARNTL, NFE2, RCOR1, CEBPB, NR3C1, KMT2A, CREB1, TBL1XR1, GRHL2, ZNF652, GABPB1, SPI1, MIXL1, TFE3, HBP1, IRF1, HDAC2, GATA2, ZNF644, ZNF777, FLI1, DRAP1, ZGPAT, RELB, EP400, NFIL3, MRTFB, ETV5, RUNX1, THAP11, BCL6, SMC1A, HDAC1, CEBPA, NKX2-2, MAFG, SOX13, ZFX, POU4F2, SIN3A, TET2, SP5, SMARCC1, MYBL2, RARA, ZNF384, NOTCH1, PRPF4, TAF15, CREBBP, GATA4, ARNT, ZBTB10, ZNF48, PRDM9, SMAD4, CBFA2T3, NR2C1, FOS, CDK8, HMGXB4, CHD1, SUPT5H, MED1, ZNF584, GMEB1, TEAD3, KDM6B, MYB, SCRT2, PIAS1, ZNF3, TAF7, NR1H2, C11orf30, L3MBTL2, MBD1, RBM22, SP1, BCL11A, HNF4A, IKZF5, NKX2-5, ASH2L, HNRNPLL, PHIP, FOXP1, AATF, SMC3, NCOR2, STAG1, PTTG1, SKI, PAX7, TRP47, PPARG, FOXA2, MTA3, CREM, CBX3, PAF1, AGO1, MIER2, ZNF600, ZNF316, WT1, MEF2C, TCF7, ZNF580, HOXB13, ZNF318, KDM1A, YY1, RELA, JUNB, KAT2B, SP140, TCF4, HIF1A, GATA3, MGA, TAL1, MAX, NRIP1, ZNF143, AGO2, HAND2, TLE3, CEBPG, ZNF592, KLF4, NCOA3, TCF7L2, NEUROG2, TP53, PKNOX1, ZNF334, MYOD1, ELF3, PHF5A, KAT8, NFKBIZ, ARID4B, PTRF, AR, PAX3-FOXO1, ZBTB40, ZBTB26, HSF1, BRD4, JUND, CUX1, MAZ, MEF2D, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): CFAP410,FAM207A,UBE2G2,ADARB1,PFKL,PTTG1IP,HSF2BP,RRP1B,TSPEAR,TRAPPC10,ITGB2,TRPM2,ITGB2-AS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160207, ENSG00000160208, ENSG00000160218, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000175894, ENSG00000184787, ENSG00000183255, ENSG00000160255, ENSG00000227039, ENSG00000160256, ENSG00000197381,

eachgene

Deatailed information for cohesin site CDBP00421106