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Basic information

CohesinDB ID: CDBP00421108

Locus: chr21-44786700-44787596

Data sourse: GSE67783, ENCSR153HNT

Cell type: K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 58%, "4_Tx": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, NME2, FOXA1, LEO1, ATF3, ZFP64, ZBTB44, ZNF189, TP63, HDAC3, ZNF467, CDX2, MYOG, TEAD1, ESR1, CTCF, TCF12, BAF155, EP300, ZBTB20, E2F1, GLIS1, NANOG, CHD8, POU2F2, MYCN, TOP2A, ZBTB48, ERG, HOXC5, ZNF585B, ASCL1, MYC, ONECUT1, EZH1, GRHL3, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, VDR, NR3C1, CEBPB, CREB1, FEZF1, ZNF257, HDAC2, GATA2, FLI1, ZNF554, RUNX1, ZFX, PCBP2, TET2, PRDM10, CREBBP, RUNX2, GATA4, OSR2, PBX4, DAXX, ARNT, SUPT5H, MED1, ZXDB, PIAS1, ZNF3, KLF16, RBM22, BCL11A, TFAP2A, GSPT2, HNF4A, ARID1A, ZSCAN31, ASH2L, FOXP1, PRDM6, AATF, SMC3, STAG1, MLLT1, NFATC3, TRP47, CBFA2T2, ZNF283, FOXA2, TBL1X, AGO1, PAF1, WT1, HOXB13, ZNF19, RELA, YY1, NEUROD1, SP140, ZIC2, HIF1A, OTX2, GATA3, ZNF143, AGO2, TLE3, SP7, NCOA3, TCF7L2, TP53, NFKB1, ZNF843, AR, ZBTB42, ZBTB26, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): FAM207A,TSPEAR,CFAP410,TRAPPC10,ITGB2-AS1,HSF2BP,ADARB1,ITGB2,PTTG1IP,TRPM2,PFKL,RRP1B,UBE2G2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160207, ENSG00000160208, ENSG00000160218, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000175894, ENSG00000184787, ENSG00000183255, ENSG00000160255, ENSG00000227039, ENSG00000160256, ENSG00000197381,

eachgene

Deatailed information for cohesin site CDBP00421108