- Basic information
- CohesinDB ID: CDBP00421110
- Locus: chr21-44789666-44790323
-
Data sourse: GSE206145-NatGen2015, ENCSR153HNT, GSE165895
-
Cell type: K-562, Fibroblast, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 75%,
"4_Tx": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, POU2F2, MEF2B, BCL6, POU5F1, MTA3, PAF1, SOX2, SS18, HOXC5, CREBBP, JUNB, NEUROD1, MYC, RUNX3, OTX2, ATF2, BATF, SUPT5H, MITF, KLF4, ELF1, TFAP2C, NEUROG2, GRHL2, RBM22, SND1, SPI1, BAF155, NCOR1, BRD4, BCOR, FOXP1, RBPJ
- Target gene symbol (double-evidenced CRMs): ITGB2,ADARB1,PFKL,UBE2G2,TRAPPC10,TSPEAR,RRP1B,ITGB2-AS1,CFAP410,HSF2BP,PTTG1IP,TRPM2,FAM207A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160207,
ENSG00000160208,
ENSG00000160218,
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000175894,
ENSG00000184787,
ENSG00000183255,
ENSG00000160255,
ENSG00000227039,
ENSG00000160256,
ENSG00000197381,
- Related loop:
chr21:27500000-27525000~~chr21:44775000-44800000,
chr21:43350000-43375000~~chr21:44775000-44800000,
chr21:43650000-43675000~~chr21:44775000-44800000,
chr21:44075000-44100000~~chr21:44775000-44800000,
chr21:44325000-44350000~~chr21:44775000-44800000,
chr21:44337712-44340224~~chr21:44792463-44794394,
chr21:44350000-44375000~~chr21:44775000-44800000,
chr21:44475000-44500000~~chr21:44775000-44800000,
chr21:44500000-44525000~~chr21:44775000-44800000,
chr21:44505181-44506574~~chr21:44792488-44794438,
chr21:44509121-44511913~~chr21:44792385-44794491,
chr21:44509188-44511574~~chr21:44792239-44794440,
chr21:44509189-44512062~~chr21:44792150-44794532,
chr21:44509195-44511716~~chr21:44792591-44794447,
chr21:44509197-44511724~~chr21:44792559-44794303,
chr21:44509207-44511848~~chr21:44792389-44794429,
chr21:44509213-44512100~~chr21:44792156-44794493,
chr21:44509225-44511899~~chr21:44792192-44794515,
chr21:44509235-44511954~~chr21:44792155-44794858,
chr21:44509236-44511997~~chr21:44792073-44794483,
chr21:44509239-44511525~~chr21:44792488-44794374,
chr21:44509242-44511652~~chr21:44792257-44794053,
chr21:44509243-44511788~~chr21:44792303-44794463,
chr21:44509258-44511514~~chr21:44792553-44794330,
chr21:44509266-44512046~~chr21:44792219-44794436,
chr21:44509273-44511642~~chr21:44792534-44794311,
chr21:44509284-44511597~~chr21:44792564-44794485,
chr21:44509310-44511786~~chr21:44792445-44794502,
chr21:44509377-44511681~~chr21:44792242-44794455,
chr21:44509457-44512145~~chr21:44792168-44794432,
chr21:44509481-44512016~~chr21:44792235-44794464,
chr21:44509488-44511948~~chr21:44792109-44794449,
chr21:44509542-44511909~~chr21:44792296-44794494,
chr21:44509599-44512047~~chr21:44792203-44794435,
chr21:44509689-44512016~~chr21:44792155-44794487,
chr21:44509692-44511946~~chr21:44792297-44794482,
chr21:44509704-44511783~~chr21:44792291-44794265,
chr21:44509706-44511793~~chr21:44792098-44794805,
chr21:44509743-44512037~~chr21:44792110-44794473,
chr21:44509835-44511664~~chr21:44792662-44794245,
chr21:44509871-44511501~~chr21:44792580-44794252,
chr21:44509875-44511428~~chr21:44792634-44794192,
chr21:44509876-44511623~~chr21:44792577-44794368,
chr21:44509897-44511527~~chr21:44792516-44794254,
chr21:44509926-44511467~~chr21:44792610-44794266,
chr21:44510020-44511606~~chr21:44792567-44794217,
chr21:44618046-44619706~~chr21:44792109-44794449,
chr21:44618096-44619578~~chr21:44792564-44794485,
chr21:44707178-44708406~~chr21:44792109-44794449,
chr21:44754736-44756602~~chr21:44792156-44794493,
chr21:44775000-44800000~~chr21:44875000-44900000,
chr21:44775000-44800000~~chr21:44900000-44925000,
chr21:44775000-44800000~~chr21:44925000-44950000,
chr21:44775000-44800000~~chr21:45125000-45150000,
chr21:5100000-5125000~~chr21:44775000-44800000,