- Basic information
- CohesinDB ID: CDBP00421112
- Locus: chr21-44797363-44798119
-
Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
-
Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 55%,
"4_Tx": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: KLF13, FOXA2, POU5F1, PAF1, ZFX, ID3, XBP1, ZNF317, ZBTB48, ZSCAN5A, STAT1, FOXA1, HINFP, ZBTB33, ZMYND8, RBFOX2, LEO1, ERG, YY1, RELA, NEUROD1, GRHL3, OTX2, PRDM9, NR2C1, GATA1, SUPT5H, CEBPB, ZNF592, ZNF558, TRIM28, ZNF680, PIAS1, OCA2, PKNOX1, HDAC8, ZNF22, JUN, RBM22, ZHX2, AR, PTRF, GATA2, BRD4, DDX20, IRF9, PTTG1
- Target gene symbol (double-evidenced CRMs): RRP1B,FAM207A,TRPM2,ITGB2,CFAP410,ITGB2-AS1,TRAPPC10,HSF2BP,TSPEAR,PTTG1IP,PFKL,UBE2G2,ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000160207,
ENSG00000160208,
ENSG00000160218,
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000175894,
ENSG00000184787,
ENSG00000183255,
ENSG00000160255,
ENSG00000227039,
ENSG00000160256,
ENSG00000197381,
- Related loop:
chr21:27500000-27525000~~chr21:44775000-44800000,
chr21:42875000-42900000~~chr21:44800000-44825000,
chr21:42975000-43000000~~chr21:44800000-44825000,
chr21:43350000-43375000~~chr21:44775000-44800000,
chr21:43350000-43375000~~chr21:44800000-44825000,
chr21:43650000-43675000~~chr21:44775000-44800000,
chr21:44050000-44075000~~chr21:44800000-44825000,
chr21:44075000-44100000~~chr21:44775000-44800000,
chr21:44075000-44100000~~chr21:44800000-44825000,
chr21:44300000-44325000~~chr21:44800000-44825000,
chr21:44325000-44350000~~chr21:44775000-44800000,
chr21:44325000-44350000~~chr21:44800000-44825000,
chr21:44337712-44340224~~chr21:44792463-44794394,
chr21:44350000-44375000~~chr21:44775000-44800000,
chr21:44475000-44500000~~chr21:44775000-44800000,
chr21:44500000-44525000~~chr21:44775000-44800000,
chr21:44505181-44506574~~chr21:44792488-44794438,
chr21:44509121-44511913~~chr21:44792385-44794491,
chr21:44509188-44511574~~chr21:44792239-44794440,
chr21:44509189-44512062~~chr21:44792150-44794532,
chr21:44509195-44511716~~chr21:44792591-44794447,
chr21:44509197-44511724~~chr21:44792559-44794303,
chr21:44509207-44511848~~chr21:44792389-44794429,
chr21:44509213-44512100~~chr21:44792156-44794493,
chr21:44509225-44511899~~chr21:44792192-44794515,
chr21:44509235-44511954~~chr21:44792155-44794858,
chr21:44509236-44511997~~chr21:44792073-44794483,
chr21:44509239-44511525~~chr21:44792488-44794374,
chr21:44509242-44511652~~chr21:44792257-44794053,
chr21:44509243-44511788~~chr21:44792303-44794463,
chr21:44509258-44511514~~chr21:44792553-44794330,
chr21:44509266-44512046~~chr21:44792219-44794436,
chr21:44509273-44511642~~chr21:44792534-44794311,
chr21:44509284-44511597~~chr21:44792564-44794485,
chr21:44509310-44511786~~chr21:44792445-44794502,
chr21:44509377-44511681~~chr21:44792242-44794455,
chr21:44509457-44512145~~chr21:44792168-44794432,
chr21:44509481-44512016~~chr21:44792235-44794464,
chr21:44509488-44511948~~chr21:44792109-44794449,
chr21:44509542-44511909~~chr21:44792296-44794494,
chr21:44509599-44512047~~chr21:44792203-44794435,
chr21:44509689-44512016~~chr21:44792155-44794487,
chr21:44509692-44511946~~chr21:44792297-44794482,
chr21:44509704-44511783~~chr21:44792291-44794265,
chr21:44509706-44511793~~chr21:44792098-44794805,
chr21:44509743-44512037~~chr21:44792110-44794473,
chr21:44509835-44511664~~chr21:44792662-44794245,
chr21:44509871-44511501~~chr21:44792580-44794252,
chr21:44509875-44511428~~chr21:44792634-44794192,
chr21:44509876-44511623~~chr21:44792577-44794368,
chr21:44509897-44511527~~chr21:44792516-44794254,
chr21:44509926-44511467~~chr21:44792610-44794266,
chr21:44510020-44511606~~chr21:44792567-44794217,
chr21:44618046-44619706~~chr21:44792109-44794449,
chr21:44618096-44619578~~chr21:44792564-44794485,
chr21:44707178-44708406~~chr21:44792109-44794449,
chr21:44754736-44756602~~chr21:44792156-44794493,
chr21:44775000-44800000~~chr21:44875000-44900000,
chr21:44775000-44800000~~chr21:44900000-44925000,
chr21:44775000-44800000~~chr21:44925000-44950000,
chr21:44775000-44800000~~chr21:45125000-45150000,
chr21:44799344-44802391~~chr21:44874408-44876218,
chr21:44799365-44801932~~chr21:44874652-44876234,
chr21:44799372-44802443~~chr21:44874407-44876256,
chr21:44799372-44802443~~chr21:44910613-44912668,
chr21:44799372-44802443~~chr21:44931965-44934113,
chr21:44799392-44802491~~chr21:44931992-44933524,
chr21:44799411-44802024~~chr21:44845318-44847256,
chr21:44799411-44802024~~chr21:44931881-44933864,
chr21:44799420-44802311~~chr21:44874548-44876442,
chr21:44799435-44802625~~chr21:44836063-44837863,
chr21:44799443-44802060~~chr21:44931925-44933520,
chr21:44799602-44802376~~chr21:44931909-44933980,
chr21:44799651-44802591~~chr21:44845216-44847176,
chr21:44799686-44802514~~chr21:44931456-44933916,
chr21:44799696-44802591~~chr21:44910581-44912708,
chr21:44799696-44802591~~chr21:44931870-44933936,
chr21:44799706-44802994~~chr21:44930823-44933918,
chr21:44799726-44802540~~chr21:44845295-44847056,
chr21:44799726-44802540~~chr21:44873123-44876204,
chr21:44800000-44825000~~chr21:44900000-44925000,
chr21:44800000-44825000~~chr21:44925000-44950000,
chr21:44800000-44825000~~chr21:45125000-45150000,
chr21:44800000-44825000~~chr21:45325000-45350000,
chr21:44800000-44825000~~chr21:45450000-45475000,
chr21:44800017-44802385~~chr21:44874479-44876246,
chr21:44800017-44802385~~chr21:44910606-44912868,
chr21:44800017-44802385~~chr21:44930976-44933923,
chr21:44800406-44801881~~chr21:44911198-44912387,
chr21:44800498-44802680~~chr21:44931107-44933966,
chr21:44800563-44802483~~chr21:44931469-44933956,
chr21:44800595-44801781~~chr21:44931962-44933491,
chr21:5100000-5125000~~chr21:44775000-44800000,