- Basic information
- CohesinDB ID: CDBP00421122
- Locus: chr21-44831852-44833670
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Data sourse: GSE67783, GSE86191, GSE105028, GSE206145-NatGen2015, GSE206145, ENCSR153HNT
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Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, BCL6, HDAC1, MYCN, FOXA2, RUNX1T1, MEIS1, LDB1, MEF2B, MTA2, GTF2B, WT1, STAT1, FOXA1, ZNF770, MEF2C, NBN, PBX2, HOXB13, ERG, LYL1, MYC, SMARCA4, ARID1B, PRDM1, GATA3, ZEB2, GABPA, SMARCE1, MAX, CBFA2T3, TAL1, GATA1, CDK8, RCOR1, NFE2, NR2F6, VDR, ELF1, TRIM28, MYB, CEBPD, LMO2, ESR1, FEZF1, EVI1, CTCF, JUN, ELF3, SPI1, BCL11A, TBX21, LMO1, GATA6, DPF2, GATA2, RBM25, RNF2, SCRT1, BRD4, RELB, TEAD4, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 19
- Related genes and loops