- Basic information
- CohesinDB ID: CDBP00421125
- Locus: chr21-44840396-44841859
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Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 41%,
"15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, FOXA1, SUZ12, PBX2, RXRB, ZNF596, ATF3, THAP1, ZBTB5, TP63, ZNF736, KLF5, ELF1, TRIM28, SNAI2, ESR1, USF2, CTCF, E2F6, TEAD4, TFAP2C, JARID2, BRD1, ZSCAN5D, MYCN, ZNF263, TOP2A, ID3, ZBTB48, SAP130, MYC, MCM5, SMARCA4, KDM4A, GRHL3, GABPA, APC, STAT3, XRCC5, ZNF614, IKZF1, DNMT3B, HNRNPH1, NR3C1, CEBPB, SRSF3, EZH2, GABPB1, ZHX2, MXD3, FLI1, ZNF490, ETV5, PTBP1, RUNX1, ZFX, TET2, PRDM10, RARA, ARNT, ZNF48, FOS, SMARCB1, TEAD3, KDM6B, ZNF3, L3MBTL2, RBM22, ARID2, REST, ZBTB7A, HNRNPLL, BCOR, AATF, STAG1, TRP47, FOXA2, AGO1, PAF1, ZNF600, WT1, RELA, MCM3, SP140, MAX, ZNF143, AGO2, PLAG1, CEBPG, KDM5B, TP53, ELF3, AR, ZNF445, TAF1, HEXIM1, HSF1, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops
- Related gene:
- Related loop:
chr21:27500000-27525000~~chr21:44825000-44850000,
chr21:44799411-44802024~~chr21:44845318-44847256,
chr21:44799435-44802625~~chr21:44836063-44837863,
chr21:44799651-44802591~~chr21:44845216-44847176,
chr21:44799726-44802540~~chr21:44845295-44847056,
chr21:44816840-44819191~~chr21:44845055-44847370,
chr21:44817582-44819008~~chr21:44845213-44846787,
chr21:44845305-44846867~~chr21:44873085-44874364,
chr21:44845305-44846867~~chr21:44882190-44883389,
chr21:44845323-44847405~~chr21:44871275-44872729,
chr21:44845331-44847295~~chr21:44932164-44933556,