- Basic information
- CohesinDB ID: CDBP00421164
- Locus: chr21-45063992-45064287
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 50%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, TRP47, PGR, CHD8, TRIM25, FOXA2, POU5F1, MYCN, MAFG, HMGN3, ZFX, TEAD4, ZNF534, AGO1, WT1, ZBTB48, CTBP1, MAFF, SMC1A, TET2, ERG3, RBFOX2, KDM1A, ERG, RELA, YY1, ATF3, RUNX2, MYC, SMARCA4, SP140, ARNT, ZFP36, GRHL3, ATF4, ZNF48, MGA, TOP2A, STAT3, SMARCB1, IKZF1, NFE2, RCOR1, BCL6, SRSF3, TEAD1, KDM6B, NR2F1, NFE2L2, ZNF3, C11orf30, L3MBTL2, EGR2, CTCF, MAFK, SPI1, AR, DPF2, ZBTB40, ZBTB7A, HSF1, BRD4, CTBP2, JUND, E2F1, MAZ, AATF, MRTFB, SMC3, ZNF316, GTF2F1, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): ADARB1,TSPEAR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops