- Basic information
- CohesinDB ID: CDBP00421173
- Locus: chr21-45085838-45086729
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Data sourse: GSE86191, ENCSR198ZYJ, ENCSR153HNT, ENCSR404BPV
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Cell type: K-562, Neurons-H1, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 37%,
"7_Enh": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, XBP1, FOXA1, LEO1, ZFHX2, HDGF, ATF3, NFIC, RUNX3, PRDM1, ATF4, CBFB, MECOM, MITF, JMJD1C, MAF, TEAD1, TRIM28, RBM39, ETV1, LMO2, COBLL1, MLL, OCA2, ESR1, USF2, CTCF, BAF155, ARID5B, LMO1, DPF2, TRIM24, IRF4, SOX6, RAD51, TEAD4, RBPJ, EED, POU2F2, CHD8, ZSCAN5D, MYCN, ZNF263, TOP2A, ID3, RUNX1T1, CTBP1, MTA2, ZBTB17, ZBTB48, ZMYND11, STAT1, NBN, ERG2, ERG, PBX1, MYC, SMARCA4, GABPA, NKX3-1, IKZF1, LEF1, RCOR1, NR2F6, VDR, ZNF750, ESRRA, SRSF3, CEBPB, STAT5B, KMT2A, CREB1, SPI1, HES1, HDAC2, GATA2, SSRP1, ZNF777, MXI1, RELB, HCFC1R1, NFYB, RUNX1, BCL6, HDAC1, LDB1, CEBPA, SIN3A, ZFX, SMAD3, ERG3, TRIM22, NOTCH1, RUNX2, ZNF184, DAXX, PBX4, ARNT, ZEB2, PBX3, CBFA2T3, NR2C1, FOS, CDK8, MYB, PIAS1, L3MBTL2, EVI1, STAT5A, KLF16, RBM22, USF1, BCL11A, ARID1A, TCF3, BCOR, SMC3, MLLT1, STAG1, SKI, CBFA2T2, FOXA2, CBX3, NFATC1, WT1, ZBTB33, MEF2C, CDK9, BCL3, YY1, RELA, TARDBP, NEUROD1, JUNB, BRG1, SP140, TCF4, HIF1A, OTX2, GATA3, BHLHE22, TAL1, MAX, SPIB, ZNF143, CBX2, TLE3, PLAG1, NCOA3, NR2F2, NR2F1, TCF7L2, TP53, ZBTB6, EGR2, TBX21, BHLHE40, AR, ZBTB42, NCOR1, RNF2, BRD4, JUND, IKZF2, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): ADARB1,TRAPPC10,FAM207A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops