- Basic information
- CohesinDB ID: CDBP00421176
- Locus: chr21-45091483-45092239
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Data sourse: ENCSR000EFJ, GSE86191, ENCSR000HPG, ENCSR000BLY, ENCSR000EHW, ENCSR000EHX, ENCSR153HNT, GSE83726, GSE116344
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Cell type: RH4, HCT-116, IMR-90, SK-N-SH, K-562
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 38%,
"7_Enh": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, XBP1, FOXA1, LEO1, ZFHX2, ATF3, NFIC, RUNX3, PRDM1, IKZF3, MITF, ELF1, SNAI2, ESR1, OCA2, PITX3, USF2, CTCF, JUN, GATA6, RFX5, RAD51, ZNF528, SMC1, EED, GLIS1, CHD8, ZSCAN5D, ZNF263, MYCN, TOP2A, CDK7, ZBTB17, ZBTB48, ZNF485, ERG2, SP4, ERG, ETS1, MYC, SMARCA4, RAD21, GABPA, RCOR1, NR3C1, CEBPB, KMT2A, BMPR1A, EBF3, SPI1, GATA2, FLI1, MXI1, MRTFB, RUNX1, BCL6, EZH2phosphoT487, AFF4, ZFX, CBX8, ERG3, TWIST1, CREBBP, ZNF384, RARA, RUNX2, ARNT, PRDM9, CBFA2T3, CHD1, MYB, USF1, BCL11A, ASH2L, PHIP, BCOR, TCF3, SMC3, STAG1, CBFA2T2, MEF2B, PPARG, CHD2, NFATC1, ZNF600, WT1, YY1, RELA, NEUROD1, JUNB, SP140, ZIC2, HIF1A, TCF4, OTX2, BHLHE22, ZNF519, TAL1, MAX, GATA1, HAND2, CBX2, PLAG1, NR2F2, TP53, PKNOX1, ZNF334, NFKB1, MYOD1, EGR2, BRD2, ELF3, AR, PAX3-FOXO1, ZBTB42, RNF2, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): ADARB1,FAM207A,TRAPPC10
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops