Deatailed information for cohesin site CDBP00421184

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  • Basic information
  • CohesinDB ID: CDBP00421184
  • Locus: chr21-45105742-45106561
  • Data sourse: GSE206145-GSE177045, ENCSR153HNT, GSE98367
  • Cell type: K-562, MCF-7, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: Mau2,SA1,SMC1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS,Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 85% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 42%, "7_Enh": 34%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, LEO1, MLL4, ZFHX2, HDGF, NFIC, RUNX3, CHD7, MECOM, PAX5, SFPQ, ZNF629, KLF5, TEAD1, TRIM28, ZNF557, KLF6, ETV1, SNAI2, LMO2, ESR1, OCA2, ZNF561, CTCF, TCF12, SND1, BAF155, EP300, JUN, ZNF695, ZNF423, ZNF528, SMC1, KLF3, RBPJ, EED, TFAP2C, GLIS1, POU2F2, CHD8, NANOG, MYCN, BRD3, TOP2A, RUNX1T1, CTBP1, MTA2, ZMYND11, ZNF317, ZBTB48, STAT1, ZBTB17, ERF, NBN, ERG2, HNF4G, ERG, ZNF597, NFKB2, ETS1, MYC, ZBTB8A, SMARCA4, ZNF2, ZNF341, GRHL3, RXRA, GABPA, STAT3, SOX10, NKX3-1, IKZF1, NR3C1, KMT2A, CREB1, EZH2, FEZF1, GRHL2, EBF3, SPI1, IRF1, ZNF257, HDAC2, GATA2, ZNF182, GATAD2B, FLI1, HCFC1, RELB, NCOA2, RUNX1, BCL6, EZH2phosphoT487, NKX2-2, CRY1, AFF4, ZFX, ZNF335, SMAD3, ZNF770, ERG3, TRIM22, ZNF18, PRDM10, SMARCC1, CREBBP, ZNF35, ZNF384, RUNX2, OSR2, ARNT, DAXX, PBX4, ATF2, PBX3, FOXM1, ETV6, FOS, ZNF10, MED1, ZXDB, MYB, ZNF680, PIAS1, SCRT2, ZMYM3, ZNF3, EVI1, TBX5, ZNF22, RBM22, BCL11A, NIPBL, SP1, REST, ARID1A, ASH2L, PHIP, TCF3, FOXP1, BCOR, PRDM6, ZNF337, SMC3, ZNF34, STAG1, MLLT1, MEF2B, FOXA2, EBF1, CREM, PAF1, SS18, ZNF600, ZNF692, ZSCAN16, WT1, FOXF1, ZNF574, MEF2C, TCF7, HOXB13, BCL3, YY1, RELA, TARDBP, NEUROD1, AHR, BRG1, ZNF610, SP140, ZIC2, HIF1A, ZFP36, TCF4, OTX2, GATA3, BATF, TAL1, MAX, SPIB, NRIP1, HAND2, TLE3, TCF7L2, NR2F1, TP53, PKNOX1, NFKB1, EGR2, ELF3, ZNF843, BRD2, ARRB1, TBX21, BHLHE40, AR, EGLN2, ZBTB42, IKZF2, BRD4, SCRT1, MAZ, ZNF316
  • Target gene symbol (double-evidenced CRMs): TRAPPC10,ADARB1,FAM207A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 9
  • Number of somatic mutations (non-coding): 3
  • Related genes and loops
  • Related gene: ENSG00000160218, ENSG00000160256, ENSG00000197381,
  • Related loop: chr21:44075000-44100000~~chr21:45100000-45125000, chr21:44950000-44975000~~chr21:45100000-45125000, chr21:45000000-45025000~~chr21:45100000-45125000, chr21:45100000-45125000~~chr21:45200000-45225000, chr21:45101917-45103625~~chr21:45127837-45129997, chr21:45102083-45103514~~chr21:45127466-45129726, chr21:5100000-5125000~~chr21:45100000-45125000,
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