- Basic information
- CohesinDB ID: CDBP00421187
- Locus: chr21-45112347-45112730
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Data sourse: ENCSR000EFJ, GSE67783, GSE101921, ENCSR153HNT, GSE103477
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Cell type: HCAEC, IMR-90, HSPC, K-562, THP-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 40%,
"15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, CBX5, XBP1, FOXA1, LEO1, PBX2, ZFHX2, TFAP4, HDGF, TSC22D4, LYL1, ATF3, NFIC, BMI1, CTCFL, RUNX3, CBFB, EGR1, MECOM, SMARCE1, PAX5, ZSCAN4, TP63, ZNF320, ZNF736, BACH2, JMJD1C, MAF, KLF5, ELF1, TRIM28, ZNF557, BCLAF1, ETV1, NFE2L2, TEAD1, ZNF217, ESR1, LMO2, TP73, MLL, CTCF, TCF12, JUN, EP300, ARID5B, KLF1, LMO1, BAF155, E4F1, MNT, DPF2, PAX8, E2F6, TRIM24, IRF4, SOX6, RAD51, SMC1, TEAD4, KMT2B, RBPJ, EED, TFAP2C, POU2F2, CHD8, BRD1, ZSCAN5D, ZNF263, MYCN, CDK7, ID3, RUNX1T1, CTBP1, MTA2, ZNF317, ZBTB48, DUX4, STAT1, SRF, NBN, ARID3A, ERG2, TBP, ERG, CHD4, PBX1, OGG1, ZNF597, ETS1, MYC, ZNF341, SMARCA4, ARID1B, RAD21, GRHL3, RXRA, NKX2-1, FOXK2, GABPA, STAT3, IKZF1, RCOR1, LEF1, CD74, NFE2, NR2F6, VDR, NR3C1, CEBPB, SRSF3, TERF2, STAT5B, NFRKB, KMT2A, CREB1, TBL1XR1, GRHL2, GABPB1, ZHX2, SPI1, HES1, IRF1, HDAC2, SSRP1, INTS13, GATA2, GATAD2B, ZNF182, ZSCAN29, FLI1, SREBF1, NR2C2, ZNF766, RELB, MRTFB, ATF1, RUNX1, BCL6, SMC1A, HDAC1, EZH2phosphoT487, CEBPA, NKX2-2, SIN3A, ZFX, SMAD3, TET2, ERG3, TRIM22, PRDM10, MEF2A, CREBBP, ZBTB2, NOTCH1, RARA, RUNX2, ARNT, DAXX, CBX3, ATF2, ZEB2, PBX3, NCAPH2, ETV6, FOS, CDK8, FOXM1, NR2C1, SMARCB1, MED1, CBFA2T3, ZEB1, PML, KDM6B, MYB, SCRT2, TERF1, NCOA1, L3MBTL2, EVI1, STAT5A, KLF16, MAFK, NIPBL, SP1, BCL11A, NR4A1, REST, ZBTB7A, ATF7, ZHX1, ASH2L, PHIP, MBD2, TCF3, BCOR, FOXP1, AATF, PRDM6, SMC3, NCOR2, STAT2, MLLT1, STAG1, NFATC3, SKI, TRP47, MEF2B, ZNF316, FOXA2, ZNF207, TBL1X, CREM, NFATC1, MTA3, E2F8, CHD2, ZBED1, WT1, GTF2B, EBF1, ZNF600, ESR2, ZBTB33, MEF2C, TCF7, CDK9, HOXB13, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, ZNF148, SP140, ZFP36, SKIL, TCF4, HIF1A, BHLHE22, GATA3, OTX2, BATF, MGA, MAF1, TAL1, MAX, SPIB, ZNF143, AGO2, CBX2, CEBPG, BCL11B, ZNF592, NCOA3, NR2F2, NR2F1, TCF7L2, IRF5, TP53, PKNOX1, ZNF687, MED, EGR2, TBX21, BHLHE40, AR, ZBTB16, ZBTB40, RXR, HEXIM1, RB1, TFIIIC, HSF1, MYNN, IKZF2, BRD4, RNF2, SCRT1, CLOCK, NCOR1, MAZ, MEF2D, ZNF24, AHR, RUNX1-3
- Target gene symbol (double-evidenced CRMs): TRAPPC10,FAM207A,ADARB1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops