- Basic information
- CohesinDB ID: CDBP00421193
- Locus: chr21-45145219-45145603
-
Data sourse: GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 43%,
"15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, BCL6, ZSCAN5D, MYCN, ZFX, ZNF600, XBP1, ZBTB48, WT1, ESR2, TET2, LEO1, ERG, MYC, SP140, PAX5, MAX, GATA1, ZNF264, MYB, NR2F1, ZNF3, ESR1, CTCF, HSF1, BRD4, MAZ, HCFC1R1
- Target gene symbol (double-evidenced CRMs): DNMT3L,PFKL,TRPM2,TSPEAR,ITGB2,POFUT2,UBE2G2,FAM207A,SLC19A1,COL6A2,TRAPPC10,ADARB1,COL18A1,PCBP3,ITGB2-AS1,PTTG1IP,SUMO3,CFAP410
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000160218,
ENSG00000142182,
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000175894,
ENSG00000184787,
ENSG00000184900,
ENSG00000183255,
ENSG00000160255,
ENSG00000227039,
ENSG00000160256,
ENSG00000197381,
ENSG00000186866,
ENSG00000182871,
ENSG00000173638,
ENSG00000183570,
ENSG00000142173,
- Related loop:
chr21:41425000-41450000~~chr21:45125000-45150000,
chr21:44075000-44100000~~chr21:45125000-45150000,
chr21:44250000-44275000~~chr21:45125000-45150000,
chr21:44325000-44350000~~chr21:45125000-45150000,
chr21:44350000-44375000~~chr21:45125000-45150000,
chr21:44475000-44500000~~chr21:45125000-45150000,
chr21:44500000-44525000~~chr21:45125000-45150000,
chr21:44575000-44600000~~chr21:45125000-45150000,
chr21:44775000-44800000~~chr21:45125000-45150000,
chr21:44800000-44825000~~chr21:45125000-45150000,
chr21:44850000-44875000~~chr21:45125000-45150000,
chr21:44875000-44900000~~chr21:45125000-45150000,
chr21:44925000-44950000~~chr21:45125000-45150000,
chr21:44950000-44975000~~chr21:45125000-45150000,
chr21:44975000-45000000~~chr21:45125000-45150000,
chr21:45000000-45025000~~chr21:45125000-45150000,
chr21:45125000-45150000~~chr21:45225000-45250000,
chr21:45125000-45150000~~chr21:45250000-45275000,
chr21:45125000-45150000~~chr21:45275000-45300000,
chr21:45125000-45150000~~chr21:45300000-45325000,
chr21:45125000-45150000~~chr21:45325000-45350000,
chr21:45125000-45150000~~chr21:45425000-45450000,
chr21:45125000-45150000~~chr21:45450000-45475000,
chr21:45125000-45150000~~chr21:45500000-45525000,
chr21:45125000-45150000~~chr21:45525000-45550000,
chr21:45125000-45150000~~chr21:45550000-45575000,
chr21:45125000-45150000~~chr21:45575000-45600000,
chr21:45125000-45150000~~chr21:45750000-45775000,
chr21:45125000-45150000~~chr21:45800000-45825000,
chr21:45125000-45150000~~chr21:45825000-45850000,
chr21:45125000-45150000~~chr21:45875000-45900000,
chr21:45125000-45150000~~chr21:45900000-45925000,
chr21:45125000-45150000~~chr21:46100000-46125000,
chr21:45139534-45141238~~chr21:45438384-45440554,
chr21:45139554-45141260~~chr21:45438127-45440654,
chr21:45139554-45141260~~chr21:45817765-45819179,
chr21:45139554-45141260~~chr21:45819453-45821601,
chr21:45139555-45141248~~chr21:45438460-45440575,
chr21:45139555-45141248~~chr21:45595927-45597822,
chr21:45139555-45141248~~chr21:45819512-45821569,
chr21:45139579-45141230~~chr21:45438202-45440761,
chr21:45139601-45141264~~chr21:45438059-45440543,
chr21:45139623-45141236~~chr21:45438345-45440658,
chr21:45139624-45141292~~chr21:45438383-45440733,
chr21:45139624-45141292~~chr21:45879491-45881481,
chr21:45139629-45141295~~chr21:45438049-45440695,
chr21:45139650-45141317~~chr21:45438318-45440592,
chr21:45139658-45141304~~chr21:45438366-45440780,
chr21:45139673-45141222~~chr21:45438105-45440682,
chr21:45139688-45141261~~chr21:45438098-45440775,
chr21:45139688-45141261~~chr21:45817813-45819059,
chr21:45139688-45141261~~chr21:45819215-45821572,
chr21:45139693-45141316~~chr21:45269360-45271607,
chr21:45139694-45141242~~chr21:45438439-45440623,
chr21:45139699-45141285~~chr21:45235955-45237401,
chr21:45139699-45141285~~chr21:45438142-45440624,
chr21:45139699-45141285~~chr21:45818578-45821611,
chr21:45139700-45141225~~chr21:45438474-45440647,
chr21:45139703-45141220~~chr21:45438433-45440517,
chr21:45139703-45141220~~chr21:45819757-45821509,
chr21:45139731-45141427~~chr21:45236007-45237339,
chr21:45139731-45141427~~chr21:45438417-45440836,
chr21:45139731-45141427~~chr21:45818438-45821813,
chr21:45139732-45141221~~chr21:45269444-45271544,
chr21:45139734-45141308~~chr21:45438099-45440648,
chr21:45139734-45141308~~chr21:45819513-45821757,
chr21:45139737-45141278~~chr21:45308098-45309917,
chr21:45139737-45141278~~chr21:45438575-45440579,
chr21:45139742-45141196~~chr21:45308481-45309869,
chr21:45139742-45141196~~chr21:45438737-45440429,
chr21:45139752-45141201~~chr21:45438594-45440402,
chr21:45139756-45141227~~chr21:45256456-45257780,
chr21:45139756-45141227~~chr21:45286276-45287465,
chr21:45139756-45141227~~chr21:45427127-45428797,
chr21:45139756-45141227~~chr21:45438129-45440499,
chr21:45139756-45141227~~chr21:45477292-45479145,
chr21:45139756-45141227~~chr21:45595881-45597823,
chr21:45139756-45141227~~chr21:45819438-45821567,
chr21:45139756-45141227~~chr21:45879726-45881542,
chr21:45139756-45141227~~chr21:45922568-45924115,
chr21:45139772-45141201~~chr21:45308090-45309979,
chr21:45139772-45141201~~chr21:45438414-45440537,
chr21:45139773-45141251~~chr21:45235891-45237378,
chr21:45139773-45141251~~chr21:45438069-45440905,
chr21:45139777-45141216~~chr21:45818539-45821603,
chr21:45139825-45141312~~chr21:45235909-45237329,
chr21:45139825-45141312~~chr21:45438277-45440446,
chr21:45139825-45141312~~chr21:45819878-45821577,
chr21:45139844-45141294~~chr21:45438469-45440424,
chr21:45139849-45141273~~chr21:45308581-45309918,
chr21:45139849-45141273~~chr21:45438598-45440391,
chr21:45139858-45141276~~chr21:45438511-45440385,
chr21:45139859-45141236~~chr21:45438572-45440279,
chr21:45139859-45141236~~chr21:45879927-45881351,
chr21:45139873-45141121~~chr21:45438877-45440262,
chr21:45139887-45141209~~chr21:45438578-45440270,
chr21:45150000-45175000~~chr21:45250000-45275000,
chr21:45150000-45175000~~chr21:45275000-45300000,
chr21:45150000-45175000~~chr21:45425000-45450000,
chr21:45150000-45175000~~chr21:45450000-45475000,
chr21:45150000-45175000~~chr21:45725000-45750000,
chr21:45150000-45175000~~chr21:45800000-45825000,