- Basic information
- CohesinDB ID: CDBP00421202
- Locus: chr21-45157471-45158352
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Data sourse: ENCSR000BTU, GSE67783, GSE86191, ENCSR000BLY, ENCSR000EHW, ENCSR153HNT, ENCSR000EHX
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Cell type: HCT-116, Ishikawa, SK-N-SH, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 60%,
"15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, ZNF496, ZSCAN5C, SOX2, ZNF621, FOXA1, SUZ12, LEO1, PBX2, ZFHX2, HDGF, NFIC, CHD7, ZNF322, ZNF444, TP63, MITF, ZNF467, CDC5L, BCLAF1, ESR1, PITX3, USF2, CTCF, TCF12, EP300, KLF1, E4F1, MNT, GLI4, ZNF423, ZNF512B, ZNF776, TEAD4, PDX1, TFAP2C, RBPJ, EHMT2, GLIS1, YBX1, POU2F2, CHD8, MYCN, ZNF239, ZNF263, ID3, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ZNF317, STAT1, ZSCAN5A, NONO, SRF, ZBTB1, DDX5, ERG2, ZNF300, ERG, PBX1, MYC, RFX1, TSHZ1, FOXP2, RAD21, GABPA, ZNF8, NKX3-1, ZNF398, RCOR1, HNRNPH1, NR3C1, ESRRA, CREB1, KLF8, ARHGAP35, GRHL2, EBF3, HES1, ZNF202, HDAC2, GATA2, SSRP1, GATAD2B, ZNF146, MXI1, ZNF785, MRTFB, HDAC1, NKX2-2, LDB1, ZNF707, ZFX, POU4F2, SMAD3, ZNF473, ERG3, TET2, TWIST1, ZNF549, NOTCH1, RUNX2, SMAD2, OSR2, ARNT, NFIB, ELK1, ATF2, SMAD4, CBFA2T3, SP2, MED1, CEBPD, MYB, ZNF680, RBM22, USF1, MAFK, BCL11A, PHF20, REST, ZBTB7A, HNRNPLL, PHIP, SALL1, FOXP1, TCF3, SMC3, STAG1, FOXA2, CBX3, MTA3, CHD2, ZNF207, ZNF600, WT1, ZNF662, KDM1A, YY1, RELA, TARDBP, NEUROD1, ZNF521, ZNF282, SP140, TCF4, HIF1A, ZIC2, ZFP36, ZNF311, TAL1, MAX, GATA1, ZNF143, HAND2, KLF4, ZNF592, NCOA3, ZNF544, NEUROG2, ZNF791, NR2F1, TP53, PKNOX1, ZNF687, ZSCAN22, NFKB1, EGR2, BHLHE40, AR, PAX3-FOXO1, TAF1, RXR, ZFP41, ZBTB42, ZNF366, EGR1, ZBTB26, BRD4, MAZ, ZSCAN23, AHR
- Target gene symbol (double-evidenced CRMs): COL18A1,PCBP3,ADARB1,POFUT2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000197381,
ENSG00000186866,
ENSG00000182871,
ENSG00000183570,
- Related loop:
chr21:45150000-45175000~~chr21:45250000-45275000,
chr21:45150000-45175000~~chr21:45275000-45300000,
chr21:45150000-45175000~~chr21:45425000-45450000,
chr21:45150000-45175000~~chr21:45450000-45475000,
chr21:45150000-45175000~~chr21:45725000-45750000,
chr21:45150000-45175000~~chr21:45800000-45825000,
chr21:45151104-45153330~~chr21:45269360-45271607,
chr21:45151182-45153539~~chr21:45307919-45309932,
chr21:45151182-45153539~~chr21:45438127-45440654,
chr21:45151234-45153330~~chr21:45438098-45440775,
chr21:45151445-45153499~~chr21:45438460-45440575,
chr21:45151535-45153313~~chr21:45235859-45237361,
chr21:45151610-45153626~~chr21:45438417-45440836,
chr21:45151733-45153242~~chr21:45308637-45309801,
chr21:45151747-45153264~~chr21:45438277-45440446,