- Basic information
- CohesinDB ID: CDBP00421208
- Locus: chr21-45169768-45170044
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Data sourse: ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 44%,
"7_Enh": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF468, FOXO1, SOX2, XBP1, FOXA1, PBX2, ATF3, THAP1, PRDM1, MORC2, ZNF273, TP63, MITF, BACH2, BCLAF1, NFE2L2, SMAD5, ESR1, MLL, CTCF, BAF155, DPF2, TEAD4, EED, POU2F2, CHD8, ZNF263, CTBP1, MTA2, DUX4, ZSCAN5A, TBP, ONECUT1, EZH1, SMARCA4, ARID1B, GRHL3, RXRA, GABPA, NFE2, RCOR1, VDR, CREB1, EZH2, NFE2L1, ELF4, SPI1, GATA2, FLI1, MRTFB, RUNX1, MAFG, SMC1A, ZFX, ZMIZ1, SMARCC1, NOTCH1, RUNX2, NRF1, BACH1, ZEB2, FOS, SUPT5H, MED1, PML, CEBPD, PIAS1, TAF7, C11orf30, RBM22, MAFK, SP1, BCL11A, HNF4A, ATF7, PHIP, PRDM6, SMC3, STAG1, MLLT1, NFATC3, GTF2B, MAFF, WT1, HOXB13, YY1, RELA, JUNB, TAL1, GATA1, NCOA3, PKNOX1, MYOD1, PHOX2B, BRD2, BHLHE40, AR, ZBTB40, HSF1, RNF2, BRD4, ILF3, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): COL18A1,ADARB1,PCBP3,POFUT2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000197381,
ENSG00000186866,
ENSG00000182871,
ENSG00000183570,
- Related loop:
chr21:29850000-29875000~~chr21:45175000-45200000,
chr21:45150000-45175000~~chr21:45250000-45275000,
chr21:45150000-45175000~~chr21:45275000-45300000,
chr21:45150000-45175000~~chr21:45425000-45450000,
chr21:45150000-45175000~~chr21:45450000-45475000,
chr21:45150000-45175000~~chr21:45725000-45750000,
chr21:45150000-45175000~~chr21:45800000-45825000,