- Basic information
- CohesinDB ID: CDBP00421209
- Locus: chr21-45171104-45171438
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Data sourse: GSE86191, GSE67783, GSE83726
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Cell type: RH4, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
85% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"15_Quies": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, TRIM25, CHD8, BRD1, ZNF263, ZFX, XBP1, WT1, ZBTB48, ERG, HOXC5, RELA, YY1, ATF3, MYC, SMARCA4, RAD21, SP140, ARNT, HIF1A, GABPA, TAL1, TEAD3, KDM6B, CTCF, ARRB1, AR, TAF1, SOX4, RAD51, BRD4, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): COL18A1,ADARB1,PCBP3,POFUT2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000197381,
ENSG00000186866,
ENSG00000182871,
ENSG00000183570,
- Related loop:
chr21:29850000-29875000~~chr21:45175000-45200000,
chr21:45150000-45175000~~chr21:45250000-45275000,
chr21:45150000-45175000~~chr21:45275000-45300000,
chr21:45150000-45175000~~chr21:45425000-45450000,
chr21:45150000-45175000~~chr21:45450000-45475000,
chr21:45150000-45175000~~chr21:45725000-45750000,
chr21:45150000-45175000~~chr21:45800000-45825000,